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  1. No Access

    Article

    Lgr5-expressing chief cells drive epithelial regeneration and cancer in the oxyntic stomach

    The daily renewal of the corpus epithelium is fuelled by adult stem cells residing within tubular glands, but the identity of these stem cells remains controversial. Lgr5 marks homeostatic stem cells and ‘rese...

    Marc Leushacke, Si Hui Tan, Angeline Wong, Yada Swathi… in Nature Cell Biology (2017)

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    Article

    Lgr5 marks stem/progenitor cells in ovary and tubal epithelia

    The ovary surface epithelium (OSE) undergoes ovulatory tear and remodelling throughout life. Resident stem cells drive such tissue homeostasis in many adult epithelia, but their existence in the ovary has not ...

    Annie Ng, Shawna Tan, Gurmit Singh, Pamela Rizk, Yada Swathi… in Nature Cell Biology (2014)