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Article
Glial growth factor 2 treatment alleviates ischemia and reperfusion-damaged integrity of the blood-brain barrier through decreasing Mfsd2a/caveolin-1-mediated transcellular and Pdlim5/YAP/TAZ-mediated paracellular permeability
The impairment of blood-brain barrier (BBB) integrity is the pathological basis of hemorrhage transformation and vasogenic edema following thrombolysis and endovascular therapy. There is no approved drug in th...
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Article
Open AccessFar-reaching benefits of the consumption of conspecific eggs by neonate larvae of Harmonia axyridis (Pallas) (Coleoptera: Coccinellidae): a case study on an artificial diet
The consumption of conspecific eggs by neonate larvae is a common behavior in aphidophagous coccinellids. However, it is still unknown what far-reaching benefits can be brought to the artificial diet-reared ca...
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Article
Effects of long-term cold storage on maternal and progeny fitness of laboratory-reared Harmonia axyridis adults
Long-term cold storage is a commonly used technique in mass rearing of natural enemies, but it brings a diversity of negative effects, especially for the laboratory-reared biocontrol agents. Harmonia axyridis (Pa...
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Article
Open AccessGinkgolide B improved postoperative cognitive dysfunction by inhibiting microgliosis-mediated neuroinflammation in the hippocampus of mice
Postoperative cognitive dysfunction (POCD) are a common complication of the central nervous system following surgery and anesthesia. The specific pathogenesis and effective therapeutics of POCD need to be furt...
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Article
Open AccessObstructs-equipped apparatus reduces cannibalism and improves larval survival of the Coccinellid, Harmonia axyridis (Coleoptera: Coccinellidae)
Harmonia axyridis (Pallas) (Coleoptera: Coccinellidae) is an important biocontrol agent in native region of Asia, while its high propensity for cannibalism causes great obstacles in mass production. Provisioning ...
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Article
Functional morphology of the mouthparts of lady beetle Hippodamia variegata (Coleoptera: Coccinellidae), with reference to their feeding mechanism
The lady beetle Hippodamia variegata (Goeze, 1777) is widely distributed around the world and reported as an important natural enemy of aphids, noctuid larvae, leafhoppers, and psyllids. As feeding organs, the mo...
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Article
Open AccessInvestigating reproductive success of the ladybird beetle Harmonia axyridis from the perspective of micropyle variation
Micropyles in insects are small openings that allow sperm entry into, and the number was usually decreased on unfertilized and (or) undeveloped eggs. However, reports showed that Harmonia axyridis, a reproductive...
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Article
A novel STAT3 inhibitor negatively modulates platelet activation and aggregation
The signal transducer and activator of transcription 3 (STAT3) plays a critical role in platelet functions. This study sought to understand the effects of the STAT3 inhibitor SC99 on platelet activation and ag...
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Article
Open AccessHydrogen Sulfide and/or Ammonia Reduces Spermatozoa Motility through AMPK/AKT Related Pathways
A number of emerging studies suggest that air pollutants such as hydrogen sulfide (H2S) and ammonia (NH3) may cause a decline in spermatozoa motility. The impact and underlying mechanisms are currently unknown. B...
