152 Result(s)
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Vertebral fracture severity assessment on anteroposterior radiographs with a new semi-quantitative technique
We developed a new tool to assess the severity of osteoporotic vertebral fracture using radiographs of the spine. Our technique can be used in patient care by hel** to stratify patients with osteoporotic ver...
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Open AccessCongenital anomalies of the kidney and urinary tract: antenatal diagnosis, management and counselling of families
Congenital anomalies of the kidney and urinary tract are collectively one of the most commonly diagnosed antenatal conditions. Clinicians have several tools available to diagnose anomalies, including imaging, ...
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Open AccessThe impact of preoperative sarcopenia on postoperative ileus following colorectal cancer surgery
Sarcopenia is associated with poor short- and long-term patient outcomes following colorectal surgery. Despite postoperative ileus (POI) being a major complication following colorectal surgery, the predictive ...
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Late-Night Overeating and All-Cause and Cardiovascular Disease Mortality in Adults Aged ≥ 50: A Cohort Study
Late-night overeating (LNOE) is closely associated with many health risk factors, but whether LNOE can increase the risk of death remains unknown. Thus, the prospective cohort study aimed to investigate the re...
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Open AccessRetraction Note: A natural food sweetener with anti-pancreatic cancer properties
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Insulin Resistance-Varying Associations of Adiposity Indices with Cerebral Perfusion in Older Adults: A Population-Based Study
Excessive accumulation of adipose tissue may accelerate brain aging, but the underlying mechanisms are poorly understood. Several adiposity indices were proposed to assess obesity, while their linkage with bra...
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Should we screen for intracranial aneurysms in children with autosomal dominant polycystic kidney disease?
This is an overview of the challenges associated with screening for asymptomatic intracranial aneurysms (ICA) in children with autosomal dominant polycystic kidney disease (ADPKD). ADPKD is the most common inh...
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Rule-based natural language processing for automation of stroke data extraction: a validation study
Data extraction from radiology free-text reports is time consuming when performed manually. Recently, more automated extraction methods using natural language processing (NLP) are proposed. A previously develo...
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Relationship of frailty with excess mortality during the COVID-19 pandemic: a population-level study in Ontario, Canada
There is a paucity of the literature on the relationship between frailty and excess mortality due to the COVID-19 pandemic.
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Open AccessCross-Platform Omics Prediction procedure: a statistical machine learning framework for wider implementation of precision medicine
In this modern era of precision medicine, molecular signatures identified from advanced omics technologies hold great promise to better guide clinical decisions. However, current approaches are often location-...
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Article
Autophagy deficiency promotes lung metastasis of prostate cancer via stabilization of TWIST1
The role of autophagy in prostate cancer metastasis remains controversial, and the effects of the autophagy-related gene ATG5 on prostate cancer metastasis are poorly understood. This study aims to explore the...
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CT detects more osteoporotic endplate depressions than radiograph: a descriptive comparison of 76 vertebrae
This study analyzed elderly women who had chest radiograph and chest CT with indications other than spine disorders. Using CT images as reference, the study demonstrates that radiograph can miss a high portion...
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Osteoporotic vertebral endplate and/or cortex fracture is not always radiographically detectable
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Role of pre-operative ureteral stent on outcomes of retrograde intra-renal surgery (RIRS): systematic review and meta-analysis of 3831 patients and comparison of Asian and non-Asian cohorts
To evaluate the outcomes of pre-stented (PS) versus non-pre-stented (NPS) patients who have undergone retrograde intrarenal surgery (RIRS) for renal calculi with subgroup analysis of Asian and non-Asian cohorts.
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Open AccessAccurate classification of carotid endarterectomy indication using physician claims and hospital discharge data
Studies of carotid endarterectomy (CEA) require stratification by symptomatic vs asymptomatic status because of marked differences in benefits and harms. In administrative datasets, this classification has bee...
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Multidisciplinary quality improvement initiative to optimize acute neurovascular imaging for transient ischemic attack or minor stroke
Neurovascular imaging for patients with high-risk transient ischemic attack (TIA) or minor stroke in the emergency department (ED) with computed tomography angiography (CTA) of the head and neck is the guideli...
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Open AccessComparing regression modeling strategies for predicting hometime
Hometime, the total number of days a person is living in the community (not in a healthcare institution) in a defined period of time after a hospitalization, is a patient-centred outcome metric increasingly us...
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Open AccessSex differences in direct healthcare costs following stroke: a population-based cohort study
The economic burden of stroke on the healthcare system has been previously described, but sex differences in healthcare costs have not been well characterized. We described the direct person-level healthcare c...
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Preventive intraperitoneal hyperthermic perfusion chemotherapy for patients with T4 stage colon adenocarcinoma
Hyperthermic intraperitoneal chemotherapy (HIPEC) has been shown to be an effective treatment for peritoneal tumors; whether preventive HIPEC after radical resection for T4 stage colon adenocarcinoma could dec...
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Open AccessUsing random forests to model 90-day hometime in people with stroke
Ninety-day hometime, the number of days a patient is living in the community in the first 90 after stroke, exhibits a non-normal bucket-shaped distribution, with lower and upper constraints making its analysis...
