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Age effect on the shared etiology of glycemic traits and serum lipids: evidence from a Chinese twin study
Diabetes and dyslipidemia are among the most common chronic diseases with increasing global disease burdens, and they frequently occur together. The study aimed to investigate differences in the heritability o...
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Article
Development and validation of a novel nomogram predicting pseudohypoxia type pheochromocytomas and paragangliomas
Pseudohypoxia type (PHT) pheochromocytomas and paragangliomas (PPGLs) are more likely to metastasize and have a poor prognosis. However, application of genetic tests has many restrictions. The study aims to es...
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Article
Open AccessPredicting Progression from Normal to MCI and from MCI to AD Using Clinical Variables in the National Alzheimer’s Coordinating Center Uniform Data Set Version 3: Application of Machine Learning Models and a Probability Calculator
Clinical trials are increasingly focused on pre-manifest and early Alzheimer’s disease (AD). Accurately predicting clinical progressions from normal to MCI or from MCI to dementia/AD versus non-progression is ...
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Open AccessRole of the active cycle of breathing technique combined with phonophoresis for the treatment of patients with chronic obstructive pulmonary disease (COPD): study protocol for a preliminary randomized controlled trial
Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory lung disease characterized by coughing, the production of excess sputum, and dyspnea. Patients with excessively thick sputum may have freq...
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Article
Canopy Spectral Characteristics Under Different Backgrounds of Wetland Aquatic Vegetation
This paper presents wetland aquatic vegetation remote sensing data using laboratory experiments on irises (Iris tectorum Maxim) and a simulation of the wetland aquatic vegetation growth environment. The spectr...
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Article
Metformin reduces the relapse rate of tuberculosis patients with diabetes mellitus: experiences from 3-year follow-up
The role of metformin (MET) on treatment effect of diabetic tuberculosis (TB) patients has not been studied in China. Thus, we conducted a retrospective study to investigate whether MET exhibited more efficacy...
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Article
Empirical model for estimating vertical concentration profiles of re-suspended, sediment-associated contaminants
Vertical distribution processes of sediment contaminants in water were studied by flume experiments. Experimental results show that settling velocity of sediment particles and turbulence characteristics are th...
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Article
Erratum: Cotransplantation of bone marrow-derived mesenchymal stem cells in haploidentical hematopoietic stem cell transplantation in patients with severe aplastic anemia: an interim summary for a multicenter phase II trial results
Correction to: Bone Marrow Transplantation (2017) 52, 704–710; doi:10.1038/bmt.2016.347; published online 9 January 2017 Since the publication of this article, the authors noticed a mistake in the text of the ...
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Article
Prothionamide susceptibility testing of Mycobacterium tuberculosis using the resazurin microtitre assay and the BACTECMGIT 960 system
Resazurin microtitre assay (RMA) has been successfully used to detect minimal inhibitory concentrations (MICs) of both first-line and several second-line drugs in drug susceptibility testing (DST) of Mycobacteriu...
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Article
Cotransplantation of bone marrow-derived mesenchymal stem cells in haploidentical hematopoietic stem cell transplantation in patients with severe aplastic anemia: an interim summary for a multicenter phase II trial results
Haploidentical hematopoietic stem cell transplantation (haplo-HSCT) for severe aplastic anemia (SAA) is mainly limited by the high incidence of graft failure and GvHD. Mesenchymal stem cells (MSCs) have been s...
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Article
Loss of Dnmt3b accelerates MLL-AF9 leukemia progression
Acute myeloid leukemia (AML) is a heterogeneous hematopoietic disorder with a poor prognosis. Abnormal DNA methylation is involved in the initiation and progression of AML. The de novo methyltransferases Dnmt3a a...
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Article
Open AccessSpontaneous and strong multi-layer graphene n-do** on soda-lime glass and its application in graphene-semiconductor junctions
Scalable and low-cost do** of graphene could improve technologies in a wide range of fields such as microelectronics, optoelectronics, and energy storage. While achieving strong p-do** is relatively straig...
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Article
Altered mesenchymal niche cells impede generation of normal hematopoietic progenitor cells in leukemic bone marrow
Degeneration of normal hematopoietic cells is a shared feature of malignant diseases in the hematopoietic system. Previous studies have shown the exhaustion of hematopoietic progenitor cells (HPCs) in leukemic...
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Article
Open AccessSuperfluid and metamagnetic phase transitions in ω-deformed gauged supergravity
We study non-supersymmetric truncations of ω-deformed N = ...
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Article
Dawn-dusk scale of dipolarization front in the Earth’s magnetotail: multi-cases study
We analyze three dipolarization front (DF) events to investigate their dawn-dusk scales in the Earth’s magnetotail using the Cluster measurements in year 2007, when the spacecraft separation is about 1.8 Re (R...
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Article
Automated liquid culture system misses isoniazid heteroresistance in Mycobacterium tuberculosis isolates with mutations in the promoter region of the inhA gene
Heteroresistance in Mycobacterium tuberculosis isolates remains the major challenge for phenotypic drug susceptibility testing (DST) methods to detect drug resistance. The aim of this study was to investigate the...
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Article
Open AccessCorrelation functions in ω-deformed \( \mathcal{N}=6 \) supergravity
Gauged N = 8 ...
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Molecular and phenotypic characterization of multidrug-resistant Mycobacterium tuberculosis isolates resistant to kanamycin, amikacin, and capreomycin in China
Although second-line anti-tuberculosis (TB) injectable drugs have been widely used to improve treatment outcomes of multidrug-resistant TB (MDR-TB), little is known about the prevalence and mechanism of second...
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Article
Propagation behavior of elastic waves in one-dimensional piezoelectric/piezomagnetic phononic crystal with line defects
Using a stiffness matrix method, we investigate the propagation behaviors of elastic waves in one-dimensional (1D) piezoelectric/piezomagnetic (PE/PM) phononic crystals (PCs) with line defects by calculating e...
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Linezolid in the treatment of extensively drug-resistant tuberculosis
To investigate the linezolid (LZD) treatment outcome and correlation between in vitro susceptibility to LZD and clinical outcome.