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  1. No Access

    Article

    Modelling of overall plastic deformation in rubber-toughened polymers

    In this paper, we provide a constitutive model for overall (macroscopic) plastic deformation behavior in a rubber-toughened polymer blend. A porous plasticity theory is employed as a basis for the constitutive...

    M. Kuroda, Y. Handa, M. Ishikawa in Acta Mechanica (2004)

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    Article

    Deposition of Diamond-Like Carbon Film in a Closed-Space CH4 RF Plasma

    Deposition of diamond-like carbon (DLC) film and mass spectrometry measurements were carried out in a closed-space CH4 rf (13.56 MHz) plasma (without both gas injection and vacuum pum** during the process). At ...

    N. Mutsukura, Y. Handa in Plasma Chemistry and Plasma Processing (2002)

  3. No Access

    Article

    Alterations of Calcium/Calmodulin-Dependent Protein Kinase II Activity in Ischaemia-Induced Neuronal Death and Neuronal Protection Against Ischaemia in the Gerbil Hippocampus

     To clarify the relation between neuronal protection against ischaemia and calcium/calmodulin-dependent protein kinase II (CaM kinase II) activity, we investigated temporal alterations of the kinase activity i...

    H. Uno, H. Kobayashi, Y. Handa, M. Kabuto, T. Kubota in Acta Neurochirurgica (1999)

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    Article

    Endothelial-cell injury of the basilar artery caused by ethanol infusion in dogs

    This study in mongrel dogs was designed to observe the effects of ethanol on both endothelial cells of the basilar artery and brain function. By use of sterile surgical technique, a super-selective catheter wa...

    H. Kobayashi, H. Ide, M. Kabuto, Y. Handa, T. Kubota in Acta Neurochirurgica (1996)

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    Article

    Expression of intercellular adhesion molecule 1 (ICAM-1) on the cerebral artery following subarachnoid haemorrhage in rats

    In order to study how immune-inflammatory responses are involved in the pathogenesis of cerebral vasospasm after subarachnoid haemorrhage (SAH), the kinetics of expression of the intercellular adhesion molecul...

    Y. Handa, Te. Kubota, M. Kaneko, A. Tsuchida, H. Kobayashi in Acta Neurochirurgica (1995)

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    Article

    The influence of total body hyperthermia on brain haemodynamics and blood-brain barrier in dogs

    This study was designed to examine the influence of total body hyperthermia (TBHT) using an extracorporeal circuit with a heat exchanger on the cerebral blood flow (CBF), intracranial pressure (ICP), brain tis...

    H. Katsumura, M. Kabuto, K. Hosotani, Y. Handa, H. Kobayashi in Acta Neurochirurgica (1995)

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    Chapter and Conference Paper

    MR angiography of cerebral vasospasm in primates

    Seven Japanese monkeys were used in this study. Magnetic resonance angiography (MRA), using the time-of-flight (TOF) method, was obtained. After control studies of both MRA and conventional angiography, subara...

    H. Kobayashi, T. Tsuji, M. Kabuto, Y. Handa in Proceedings of the XV Symposium Neuroradio… (1995)

  8. No Access

    Chapter and Conference Paper

    Effect of Mannitol on Focal Cerebral Ischemia Evaluated by Magnetic Resonance Imaging

    We have evaluated the effect of mannitol on focal cerebral ischemia using T2-weighted magnetic resonance (MR) imaging and intravoxel incoherent motion (IVIM) MR imaging. The left middle cerebral artery (MCA) w...

    H. Kobayashi M. D., H. Ide, T. Kodera, Y. Handa, M. Kabuto, T. Kubota in Brain Edema IX (1994)

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    Article

    Theoretical study of a new energy extraction scheme of a chemically pumped pulsed iodine laser amplifier

    A new energy extraction scheme of a chemically pumped pulsed large-scale iodine laser based on a high-pressure pulsed singlet oxygen generator is proposed. In previous investigations only low-pressure oxygen g...

    M. Endo, K. Kodama, Y. Handa, T. Uchiyama in Applied Physics B (1993)

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    Article

    Development of the sympathetic innervation to the cerebral arterial system in neonatal rats as revealed by anterograde labeling with wheatgerm agglutinin-horseradish peroxidase

    In order to clarify the developmental pattern in the sympathetic nerve fibers innervating the cerebral arterial system during the postnatal period in rats, we labeled the postganglionic nerve fibers originatin...

    Y. Handa, Y. Nojyo, N. Tamamaki, A. Tsuchida, T. Kubota in Experimental Brain Research (1993)

  11. No Access

    Article

    Chemically pumped O2(a-X) laser

    A theoretical and experimental study was conducted aimed at achieving laser oscillation in the (a-X) electronic transition of oxygen molecules. Although this transition is highly forbidden by rigorous selection r...

    M. Endo, K. Kodama, Y. Handa, T. Uchiyama in Applied Physics B (1993)

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    Chapter and Conference Paper

    Effects of Corticosteroid and Mannitol on the Early and Developed Stage of Vasogenic Brain Edema Evaluated by Proton Relaxation Behaviour

    It is recognized that development of vasogenic type of brain edema strongly affects the morbidity in patients with head injury, in whom development of brain edema elevates intracranial pressure resulting in br...

    Y. Handa, Y. Noguchi, H. Ishii, H. Kobayashi, H. Kawano in Intracranial Pressure VIII (1993)

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    Chapter and Conference Paper

    Effects of Prostacyclin Analog (OP-2507) on Experimental Focal Cerebral Ischemia

    Prostacyclin produced in endothelial cells has vasodilating and antiplatelet activities. The effects of prostacyclin have been reported in experimental ischemic studies and in patients with ischemic stroke [3,...

    H. Kobayashi, M. Hayashi, H. Ide, Y. Handa, M. Kabuto in Intracranial Pressure VIII (1993)

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    Chapter and Conference Paper

    Plateau Waves and Cerebrospinal Fluid Circulation

    Plateau waves, as described by Lundberg [4], can often be observed in patients with increased intracranial pressure (ICP). The clinical significance as well as the pathophysiology of the plateau waves are stil...

    M. Hayashi, Y. Handa, H. Kobayashi, H. Kawano, H. Ishii in Intracranial Pressure VIII (1993)

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    Chapter and Conference Paper

    Influences of Total Body Hyperthermia by Extracorporeal Circulation on Intracranial Hemodynamics in Dogs

    There has been great interest in utilization of hyperthermia in patients with malignant neoplasms. Clinical applications of hyperthermia are classified into two categories; localized hyperthermia and total bod...

    H. Katsumura, K. Hosotani, M. Kabuto, Y. Handa, H. Kobayashi in Intracranial Pressure VIII (1993)

  16. No Access

    Chapter and Conference Paper

    Intracranial Pressure and Phosphorus-31 Magnetic Resonance Spectroscopy in Cats

    Cerebral metabolic alterations in an experimental study have been reported by many investigators. Recent advances in magnetic resonance spectroscopy (MRS) allow a non-invasive study of brain metabolism in vivo...

    H. Kobayashi, H. Ide, M. Kabuto, Y. Handa, H. Kawano in Intracranial Pressure VIII (1993)

  17. No Access

    Article

    Electrical stimulation of pelvic floor musculature by percutaneous implantable electrodes: A case report

    A forty-year-old man with reflex urinary incontinence due to spinal cord injury was treated with electrical stimulation of the pelvic floor musculature. In this case we employed percutaneous implantable electr...

    M. Ishigooka, N. Ishii, T. Hashimoto, Y. Suzuki in International Urology and Nephrology (1992)

  18. No Access

    Article

    Patterns of reinnervation of denervated cerebral arteries by sympathetic nerve fibers after unilateral ganglionectomy in rats

    In order to clarify the manner in which previously denervated cerebral arteries become reinnervated after unilateral excision of the superior cervical ganglion (SCG), we observed directly the reinnervating sym...

    Y. Handa, Y. Nojyo, M. Hayashi in Experimental Brain Research (1991)

  19. No Access

    Article

    The distribution pattern of the sympathetic nerve fibers to the cerebral arterial system in rat as revealed by anterograde labeling with WGA-HRP

    To clarify the projection route and the expansion of the terminal plexus of the sympathetic nerve fibers innervating the cerebral arterial system in rat, we labeled the postganglionic fibers originating in the...

    Y. Handa, H. Caner, M. Hayashi, N. Tamamaki, Y. Nojyo in Experimental Brain Research (1990)

  20. No Access

    Chapter and Conference Paper

    Effects of Antihypertensive Drugs on Intracranial Hypertension

    Systemic hypertension is frequently observed in patients with cerebrovascular disease, such as hypertensive intracerebral hemorrhage and subarachnoid hemorrhage, which is often associated with intracranial hyp...

    S. Hirose, Y. Handa, M. Hayashi, N. Shirasaki, H. Kobayashi in Intracranial Pressure VII (1989)

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