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Article
Open Access17q21.31 sub-haplotypes underlying H1-associated risk for Parkinson’s disease are associated with LRRC37A/2 expression in astrocytes
Parkinson’s disease (PD) is genetically associated with the H1 haplotype of the MAPT 17q.21.31 locus, although the causal gene and variants underlying this association have not been identified.
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Article
Ribosomal protein S3 associates with the TFIIH complex and positively regulates nucleotide excision repair
In mammalian cells, the bulky DNA adducts caused by ultraviolet radiation are mainly repaired via the nucleotide excision repair (NER) pathway; some defects in this pathway lead to a genetic disorder known as ...
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Article
Open AccessInvestigation of biogenic materials and ferroelectrets for energy harvesting on vibrating aircraft structures
In this publication the application of novel piezoelectric materials for energy harvesting on vibrating aircraft structures is investigated. These materials have significant advantages over conventional piezoe...
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Article
Low free T3 to free T4 ratio was associated with low muscle mass and impaired physical performance in community-dwelling aged population
In aged population, the association of thyroid hormones on physical performance, especially within their normal range, has yet to be elucidated. In this study, individuals with low serum free T3/free T4 were l...
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Article
Diet-induced obesity leads to metabolic dysregulation in offspring via endoplasmic reticulum stress in a sex-specific manner
Exposure to metabolic stress has been suggested to influence the susceptibility to metabolic disorders in offspring according to epidemiological and animal studies. Nevertheless, molecular mechanisms remain un...
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Article
TET-mediated hydroxymethylcytosine at the Pparγ locus is required for initiation of adipogenic differentiation
Adipose tissue is one of the main organs regulating energy homeostasis via energy storage as well as endocrine function. The adipocyte cell number is largely determined by adipogenesis. While the molecular mec...
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Article
Estimating the Texas Windstorm Insurance Association claim payout of commercial buildings from Hurricane Ike
Following growing public awareness of the danger from hurricanes and tremendous demands for analysis of loss, many researchers have conducted studies to develop hurricane damage analysis methods. Although rese...
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Article
High-normal free thyroxine levels are associated with low trabecular bone scores in euthyroid postmenopausal women
Trabecular bone scores (TBS) have recently been developed as a diagnostic tool to assess bone texture. We studied thyroid status and TBS in a population-based cohort and demonstrated that high-normal thyroxine...
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Article
Open AccessAngiopoietin 2 induces astrocyte apoptosis via αvβ5-integrin signaling in diabetic retinopathy
The vascular leakage in diabetic retinopathy leads to macular edema and vision loss. Although astrocyte play an important role in regulating blood-brain barrier integrity in the brain, the precise role of astr...
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Article
Interfractional variability in intensity-modulated radiotherapy of prostate cancer with or without thermoplastic pelvic immobilization
To determine the variability of patient positioning errors associated with intensity-modulated radiotherapy (IMRT) for prostate cancer and to assess the impact of thermoplastic pelvic immobilization on these e...
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Article
Enhanced antitumor immunotherapeutic effect of B-cell-based vaccine transduced with modified adenoviral vector containing type 35 fiber structures
For successful clinical tumor immunotherapy outcomes, strong immune responses against tumor antigens must be generated. Cell-based vaccines compromise one strategy with which to induce appropriate strong immun...
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Article
Open AccessThe role of thioredoxin 1 in the mycophenolic acid-induced apoptosis of insulin-producing cells
Mycophenolic acid (MPA) is one of many effective immunosuppressive drugs. However, MPA can induce cellular toxicity and impair cellular function in β-cells. To explore the effects of MPA and the relation between ...
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Article
Prevalence, awareness, treatment and control of hypertension in adults with diagnosed diabetes: The Fourth Korea National Health and Nutrition Examination Survey (KNHANES IV)
We evaluated the prevalence, awareness, treatment and control of hypertension in Korean adults with diagnosed diabetes using nationally representative data. Among subjects aged ⩾30 years who participated in th...
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Article
Set-up uncertainty during breast radiotherapy
The aim of this work was to establish a customized strategy for image-guided radiotherapy during whole breast irradiation. Risk factors associated with extensive errors were assessed.
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Article
The glucagon-like peptide-1 receptor agonist exenatide restores impaired pro-islet amyloid polypeptide processing in cultured human islets: implications in type 2 diabetes and islet transplantation
Islet amyloid, formed by aggregation of human islet amyloid polypeptide (hIAPP), is associated with beta cell death in type 2 diabetes as well as in cultured and transplanted human islets. Impaired prohIAPP pr...
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Article
Combustion characteristics of LPG and biodiesel mixed fuel in two blending ratios under compression ignition in a constant volume chamber
This study aims to investigate the combustion characteristics of mixed fuel of liquefied propane gas (LPG) and biodiesel under compression ignition (CI) in an effort to develop highly efficient and environment...
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Article
Risk factors related to interfractional variation in whole pelvic irradiation for locally advanced pelvic malignancies
The goal of the present study was to demonstrate risk factors affecting the interfractional variation in whole pelvic irradiation.
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Article
Deletion of Fas protects islet beta cells from cytotoxic effects of human islet amyloid polypeptide
Islet amyloid, which is mainly composed of human islet amyloid polypeptide (hIAPP), is a pathological characteristic of type 2 diabetes and also forms in cultured and transplanted islets. We used islet beta ce...
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Article
Assessment of genetic diversity and relationships among Coix lacryma-jobi accessions using microsatellite markers
The present study describes the assessment of genetic diversity and relationships among 79 Job’s tears (Coix lacrymajobi L.) accessions collected from China and Korea using 17 microsatellite markers. A total of 5...
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Chapter and Conference Paper
FSI Analysis of HAR Wing at Low Speed Flight Condition
Fluid-Structure coupling analysis is required to handle a interaction between the analysis of fluid mechanics and structural analysis. (In this study, the analysis of fluid mechanics is as follows: aerodynamic...