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  1. No Access

    Article

    Drug-selected complete restoration of superoxide generation in Epstein-Barr virus-transformed B cells from p47 phox -deficient chronic granulomatous disease patients by using a bicistronic retrovirus vector encoding a human multi-drug resistance gene (MDR1) and the p47 phox gene

    Chronic granulomatous disease (CGD) is a group of disorders characterized by the failure of phagocytes to produce superoxide. One-third of the cases of CGD in the USA and Europe results from defects in the gen...

    Mayumi Iwata, Hiroyuki Nunoi, Ichiro Matsuda, Shiro Kanegasaki… in Human Genetics (1998)

  2. No Access

    Chapter

    Female Reproduction in Mice Lacking the Prostaglandin F Receptor

    Female mice lacking the receptor for prostaglandin F2α (FP) do not deliver fetuses at term, although these can be successfully rescued by cesarean section. No induction of oxytocin receptor mRNA is found in the u...

    Y. Sugimoto, E. Segi, K. Tsuboi, A. Ichikawa, S. Narumiya in Vasopressin and Oxytocin (1998)

  3. No Access

    Article

    Mechanisms of collateral sensitivity to fluorouracil of a cis-diamminedichloroplatinum(II)-resistant human non-small lung cancer cell line

    A cisplatin(CDDP)-resistant subline of a human lung cancer cell line, PC-7/CDDP, was 4.7-fold more resistant to CDDP than the parent line in a colony-forming assay. The sensitivity of this cell line to anthrac...

    Y Sugimoto, Y Ohe, K Nishio, T Ohmori, T Morikage, Y Fujiwara… in British Journal of Cancer (1992)

  4. No Access

    Article

    Cross-resistance to tumour promoters in human cancer cell lines resistant to adriamycin or cisplatin

    The growth inhibitory effect of tumour promoters on human leukaemia and lung cancer cell lines was examined using the [3-(4,5 dimethylthiazol)-2, 5-diphenyl-tetrazolium bromide (MTT) assay. The four cell lines...

    K Nishio, Y Sugimoto, K Nakagawa, S Niimi, Y Fujiwara, M Bungo… in British Journal of Cancer (1990)

  5. No Access

    Article

    Inhibition of lung colonization of mouse colon 26 adenocarcinoma by recombinant mouse interferon β through a modification of platelet function

    Recombinant murine interferon β (MuIFN-β) given i.v. efficiently inhibited both pulmonary arrest and formation of lung colonies of NL-17, a highly metastatic variant of mouse colon adenocarcinoma 26. NL-17 was...

    T. Tsuruo, H. Saito, M. Watanabe, Y. Sugimoto… in Clinical & Experimental Metastasis (1990)