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Modification of the RANKL-RANK-binding site for the immunotherapeutic treatment of osteoporosis
Here, we proposed the use of mutated RANKL as an immunogen for active immunization and to induce anti-cytokine antibodies for osteoporosis treatment.
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Propagated guided image filtering for edge-preserving smoothing
This paper proposes an edge-preserving smoothing filtering algorithm based on guided image filter (GF). GF is a well-known edge-preserving smoothing filter, but is ineffective in certain cases. The proposed GF...
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Article
Relationship between paraoxonase-1 activity, carotid intima-media thickness and arterial stiffness in hypertensive patients
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Article
Allelic frequencies and heterozygosities of microsatellite markers covering the whole genome in the Korean
Microsatellite markers are an essential tool for genetic linkage analysis because of their high polymorphism content. Four hundred commercially available markers covering the entire genome were genotyped from ...
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Interaction between GNB3 C825T and ACE I/D polymorphisms in essential hypertension in Koreans
Essential hypertension (EH) is considered a typical polygenic disease, so the evaluation of gene–gene interactions rather than the determination of single gene effects is crucial to understanding any genetic i...
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The association of SNP276G>T at adiponectin gene with circulating adiponectin and insulin resistance in response to mild weight loss
The purpose of this study was to determine whether common single nucleotide polymorphisms (SNPs) at the adiponectin (ADIPOQ) locus influence changes in circulating adiponectin and the features of insulin resis...
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Genetic variation at the perilipin locus is associated with changes in serum free fatty acids and abdominal fat following mild weight loss
Perilipin (PLIN) is a class of protein-coating lipid droplets in adipocytes. We aimed to examine the association between common single-nucleotide polymorphisms (SNPs) at PLIN locus with circulating free fatty ...
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Weight loss effect on inflammation and LDL oxidation in metabolically healthy but obese (MHO) individuals: low inflammation and LDL oxidation in MHO women
Recently, a subtype of obesity characterized as a metabolically healthy but obese (MHO) individual has been identified. However, limited data are available on these MHO individuals’ metabolic and inflammatory ...
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Additive effect of the mutations in the β3-adrenoceptor gene and UCP3 gene promoter on body fat distribution and glycemic control after weight reduction in overweight subjects with CAD or metabolic syndrome
OBJECTIVE: To analyze the effects of the mutations in the β3-adrenoceptor (β3-AR) gene and/or uncoupling protein3 (UCP3) gene promoter on body fat distribution and glycemic control after mild weight reduction in ...
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Article
Impact of age on the injury pattern and survival of people with cervical cord injuries
Study design: A retrospective, follow-up study.
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Article
American Society of Colon and Rectal Surgeons 95th Annual Convention Podium and Poster Abstracts June 9–14, 1996 Seattle, Washington
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Biochemical studies of the late infantile form of metachromatic leukodystrophy
Biochemical studies from a patient with the late infantile form of metachromatic leukodystrophy are presented. Since the autopsy was performed soon after death, viable cells were isolated from brain. The purif...