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Article
Associations of PD-L1, PD-L2, and HLA class I expression with responses to immunotherapy in patients with advanced sarcoma: post hoc analysis of a phase 1/2 trial
Although immunotherapy is thought to be a promising cancer treatment, most patients do not respond to immunotherapy. In this post hoc analysis of a phase 1/2 study, associations of programmed death ligand 1 (P...
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Article
Correction to: Bilateral atypical ulnar fractures occurring after long-term treatment with bisphosphonate for 7 years and with teriparatide for 2 years: a case report
The original version of this article, published on 10 September 2020 contained a mistake.
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Article
Bilateral atypical ulnar fractures occurring after long-term treatment with bisphosphonate for 7 years and with teriparatide for 2 years: a case report
Most atypical fractures associated with the long-term treatment with bisphosphonates (BP) commonly develop in the femoral shaft or subtrochanteric region. We report a rare case of bilateral atypical ulnar frac...
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Article
Three-dimensional models of arteries constructed using multidetector-row CT images to perform pancreatoduodenectomy safely following dissection of the inferior pancreaticoduodenal artery
During a pancreatoduodenectomy (PD) it is important that the anatomy of the arcade of blood vessels in the head of the pancreas is fully understood before the surgery in order to reduce intraoperative bleeding...
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Article
Diabetes, glycaemic control and mortality risk in patients on haemodialysis: the Japan Dialysis Outcomes and Practice Pattern Study
There are few data on the target level of glycaemic control among patients with diabetes on haemodialysis. We investigated the impact of glycaemic control on mortality risk among diabetic patients on haemodial...
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Article
Increased incidence of acute graft-versus-host disease with the continuous infusion of cyclosporine A compared to twice-daily infusion
We retrospectively compared the incidence of acute graft-versus-host disease (GVHD) before and after September 1999, when we changed the mode of cyclosporine A (CsA) administration from twice-daily infusions (...
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Article
Male predominance among Japanese adult patients with late-onset hemorrhagic cystitis after hematopoietic stem cell transplantation
Late-onset hemorrhagic cystitis (LHC) after hematopoietic stem cell transplantation (HSCT) is mainly caused by viral infections. We retrospectively analyzed the records of 141 Japanese adult patients who under...
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Article
Elevated circulating soluble CD40 ligand in patients with mixed connective tissue disease
Abnormalities of CD40 ligand have been demonstrated in various kinds of diseases. Our objective was to determine serum soluble CD40 ligand (sCD40L) levels in patients with mixed connective tissue disease (MCT...
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Article
Reduced peritoneal protein selectivity may indicate peritoneal fibrosis in CAPD patients
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Article
Immunosuppressive therapy for patients with refractory anemia
Trials of immunosuppressive therapy have been reported in some case reports of hypoplastic myelodysplastic syndrome (MDS). In this study, we gave immunosuppressive therapies to eight patients with normo- or h...
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Article
Correlation between HHV-6 infection and skin rash after allogeneic bone marrow transplantation
We investigated whether a causal relationship exists between human herpesvirus 6 (HHV-6) and skin rash resembling acute graft-versus-host disease (GVHD) following bone marrow transplantation (BMT). Isolation o...
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Article
Management of complications after partial hepatic resection in a hemodialysis patient with severe hepatomegaly caused by autosomal dominant polycystic kidney disease
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Article
Serial analysis of matrix metalloproteinase-2 in dialysate of rat sclerosing peritonitis models
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Article
Treatment of myelodysplastic syndromes
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Article
Monitoring four herpesviruses in unrelated cord blood transplantation
Cord blood transplantation, which has lower risk of graft-versus-host disease than bone marrow transplantation, might have higher risk of infections. A system to quantify four herpesviruses, CMV, human herpesv...
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Article
Acquired Pelger–Huët anomaly in association with concomitant tacrolimus and fluconazole therapy following allogeneic bone marrow transplantation
A 38-year-old Japanese woman with severe aplastic anemia received an allogeneic bone marrow transplant from her serologically HLA-identical father. Cyclosporine and methotrexate were administered to prevent gr...
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Article
The tumor-bearing state induces augmented responses of organ-associated lymphocytes to high-dose interleukin-2 therapy in mice
A high-dose bolus regimen for interleukin(IL)-2 administration to cancer patients frequently causes serious side-effects in which various organs are involved. In order to reveal the mechanism of toxicities as...
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Chapter and Conference Paper
Therapeutic Strategy for Advanced Hepatocellular Carcinoma Using Systemic Interleukin-2 Infusion and Local Low-Dose Irradiation
In two cases of unresectable HCC with multiple lesions, in which TAE was not indicated due to the vascular abnormality or allergy against iodide contrast medium, combination therapy with systemic low-dose IL-2...
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Article
Surgical treatment of cavernous angioma involving the brainstem and review of the literature
Five cases of symptomatic cavernous angioma involving the brainstem are reported. Magnetic resonance (MR) imaging is of greatest value in the diagnosis and for surgical indication. All cases were treated by ra...
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Article
Low-dose aclarubicin in blastic transformation of essential thrombocythemia
We attempted treatment with low-dose aclarubicin (ACR), a new anthracycline, in a 66-year-old man with blastic transformation of essential thrombocythemia (ET). Two courses of ACR (20 mg/day x 7 days) were giv...