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1,921 Result(s)
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Open AccessIL-4/IL-4R axis signaling drives resistance to immunotherapy by inducing the upregulation of Fcγ receptor IIB in M2 macrophages
In recent years, immunotherapy, particularly PD-1 antibodies, have significantly enhanced the outcome of gastric cancer patients. Despite these advances, some patients do not respond well to treatment, highlig...
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Open AccessResearch Progress on Bio-inspired Flap**-Wing Rotor Micro Aerial Vehicle Development
Flap**-wing rotor (FWR) is an innovative bio-inspired micro aerial vehicle capable of vertical take-off and landing. This unique design combines active flap** motion and passive wing rotation around a vert...
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Open AccessCorrection to: Exogenous Adenosine Antagonizes Excitatory Amino Acid Toxicity in Primary Astrocytes
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Open AccessThe neutrino force in neutrino backgrounds: Spin dependence and parity-violating effects
The neutrino force results from the exchange of a pair of neutrinos. A neutrino background can significantly influence this force. In this work, we present a comprehensive calculation of the neutrino force in ...
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Open AccessEffects of tea infusion on selenium uptake in grapevine
Increased selenium (Se) content in fruits can supply Se in human body, but the effects of teas on the Se uptake in fruit trees are unknown. The effects of infusions of four teas (green, black, dark, and white)...
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Open AccessReining in the Behemoths for the Common Good? An Analysis of State Control of State-Owned Enterprises and the Pathway to Better Governance in China
The state-owned enterprise (SOE) is the most significant business form in China. In the planned economy era, the state employed SOEs to implement economic policy and to provide employment opportunities. After ...
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Open AccessAuthor Correction: Ballistic analysis of high-performance armor steel by numerical simulation
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Open AccessEpigenetic regulation of DNA repair gene program by Hippo/YAP1-TET1 axis mediates sorafenib resistance in HCC
Hepatocellular carcinoma (HCC) is a malignancy that occurs worldwide and is generally associated with poor prognosis. The development of resistance to targeted therapies such as sorafenib is a major challenge ...
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Open AccessComparison of the clinical efficacy and prognosis of the two techniques for treating partial articular-sided supraspinatus tendon tears under arthroscopy
At present, shoulder arthroscopy is usually used for treatment of rotator cuff injuries. There is still debate over the precise technique of using shoulder arthroscopy to treat partial articular-sided supraspi...
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Open AccessCorrection: Impact of non-pharmaceutical interventions during COVID-19 on future influenza trends in Mainland China
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Open AccessEnhancement of endothelial function and attenuation of portal vein injury using mesenchymal stem cells carrying miRNA-25-3p
The aims of this study were to determine whether human umbilical cord mesenchymal stem cells (hucMSCs) modified by miRNA-25-3p (miR-25-3p) overexpression could promote venous endothelial cell proliferation and...
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Open AccessManagement and treatment of severe immune-related hepatotoxicity based on clinical and pathological characteristics
The management of severe immune-related hepatotoxicity (irH) needs to be further optimized. This study aims to analyze the clinical characteristics of severe irH; improve the therapeutic strategy, especially s...
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Open AccessRemote ischemic conditioning prevents ischemic cerebrovascular events in children with moyamoya disease: a randomized controlled trial
Moyamoya disease (MMD) is a significant cause of childhood stroke and transient ischemic attacks (TIAs). This study aimed to assess the safety and efficacy of remote ischemic conditioning (RIC) in children wit...
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Open AccessCorrection: Genomic alterations related to HPV infection status in a cohort of Chinese prostate cancer patients
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Open AccessSelf-assembled copper-based nanoparticles for enzyme catalysis-enhanced chemodynamic/photodynamic/antiangiogenic tritherapy against hepatocellular carcinoma
As an emerging cancer treatment strategy, reactive oxygen species-based tumor catalytic therapies face enormous challenges due to hypoxia and the overexpression of glutathione (GSH) in the tumor microenvironme...
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Open AccessDeciphering spatial domains from spatial multi-omics with SpatialGlue
Advances in spatial omics technologies now allow multiple types of data to be acquired from the same tissue slice. To realize the full potential of such data, we need spatially informed methods for data integr...
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Open AccessGWAS combined with QTL map** reveals the genetic loci of leaf morphological characters in Nicotiana tabacum
Leaf morphology plays a crucial role in photosynthetic efficiency and yield potential in crops. Cigar tobacco plants, which are derived from common tobacco (Nicotiana tabacum L.), possess special leaf characteris...
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Open AccessCompletion rates and myelosuppression degrees of cancer patients receiving radiotherapy or chemoradiotherapy unchanged regardless of delay duration after Omicron infection
This study aimed to investigate impacts of Omicron infection on cancer patients in China. A retrospective study was conducted, including 347 cancer patients undergoing radiotherapy or chemoradiotherapy between...
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Open AccessCassini spacecraft reveals global energy imbalance of saturn
The global energy budget is pivotal to understanding planetary evolution and climate behaviors. Assessing the energy budget of giant planets, particularly those with large seasonal cycles, however, remains a c...
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Open AccessGFPT2 expression is induced by gemcitabine administration and enhances invasion by activating the hexosamine biosynthetic pathway in pancreatic cancer
Our previous studies revealed a novel link between gemcitabine (GEM) chemotherapy and elevated glutamine-fructose-6-phosphate transaminase 2 (GFPT2) expression in pancreatic cancer (PaCa) cells. GFPT2 is a rat...