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Article
Open AccessNUP43 promotes PD-L1/nPD-L1/PD-L1 feedback loop via TM4SF1/JAK/STAT3 pathway in colorectal cancer progression and metastatsis
Programmed cell death-ligand 1 (PD-L1) has a significant role in tumor progression and metastasis, facilitating tumor cell evasion from immune surveillance. PD-L1 can be detected in the tumor cell nucleus and ...
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Article
Computational design of three-dimensional RNA structure and function
RNA nanotechnology seeks to create nanoscale machines by repurposing natural RNA modules. The field is slowed by the current need for human intuition during three-dimensional structural design. Here, we demons...
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Article
Laser fluence dependence of ripple formation on fused silica by femtosecond laser irradiation
Laser-induced periodic surface structures (LIPSS, ripples) have attracted great attentions in the fields of surfaces and interfaces, yet their origin still remains puzzling, especially for dielectrics. In this...
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Article
The solution structural ensembles of RNA kink-turn motifs and their protein complexes
XSI analysis of two RNA kink-turn motifs, KtA and KtB, in a range of solution concentrations and in the presence of the kink-turn protein partner L7Ae reveals a restricted conformational ensemble that is regul...
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Article
Open AccessFemtosecond laser rapid fabrication of large-area rose-like micropatterns on freestanding flexible graphene films
We developed a simple, scalable and high-throughput method for fabrication of large-area three-dimensional rose-like microflowers with controlled size, shape and density on graphene films by femtosecond laser ...
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Article
Hydrodynamic simulation of ultrashort pulse laser ablation of gold film
The electron collision frequency in a hydrodynamic model was improved to match the laser energy absorbed with experimental data. The model calculation was used to investigate the ablation depth and the depende...
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Article
Endoscopic resection of a huge Brunner’s gland adenoma
Brunner’s gland adenoma is a rare tumour of the duodenum, which is usually benign. A 71-year-old woman presenting with epigastric pain, upper gastrointestinal haemorrhage and melaena was reported in this paper...