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Article
Open AccessAssociation between sedentary behavior, screen time and metabolic syndrome among Chinese children and adolescents
The aim of the study was to investigate the relationship between sedentary behavior, screen time and MetS among Chinese children and adolescents aged 7–17 years. Data was obtained from the China National Nutri...
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Article
Open AccessDevelopment and validation of a nomogram for assessing survival in acute exacerbation of chronic obstructive pulmonary disease patients
Early prediction of survival of hospitalized acute exacerbations of chronic obstructive pulmonary disease (AECOPD) patients is vital. We aimed to establish a nomogram to predict the survival probability of AEC...
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Article
Open AccessShuttle peptide delivers base editor RNPs to rhesus monkey airway epithelial cells in vivo
Gene editing strategies for cystic fibrosis are challenged by the complex barrier properties of airway epithelia. We previously reported that the amphiphilic S10 shuttle peptide non-covalently combined with CR...
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Article
Open AccessGenome-wide association study exploring the genetic architecture of eggshell speckles in laying hens
Eggshell speckle phenotype is an important trait in poultry production because they affect eggshell quality. However, the genetic architecture of speckled eggshells remains unclear. In this study, we determine...
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Article
Open AccessIdentification of candidate genomic regions for egg yolk moisture content based on a genome-wide association study
Eggs represent important sources of protein and are widely loved by consumers. Egg yolk taste is an important index for egg selection, and the moisture content of the egg yolk affects the taste. To understand ...
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Article
Open AccessDNA methylome and transcriptome identified Key genes and pathways involved in Speckled Eggshell formation in aged laying hens
The quality of poultry eggshells is closely related to the profitability of egg production. Eggshell speckles reflect an important quality trait that influences egg appearance and customer preference. However,...
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Article
Open AccessZebrafish: an efficient vertebrate model for understanding role of gut microbiota
Gut microbiota plays a critical role in the maintenance of host health. As a low-cost and genetically tractable vertebrate model, zebrafish have been widely used for biological research. Zebrafish and humans s...
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Article
Open AccessRole of hippocampal location and radiation dose in glioblastoma patients with hippocampal atrophy
The hippocampus is a critical organ for irradiation. Thus, we explored changes in hippocampal volume according to the dose delivered and the location relative to the glioblastoma.
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Article
Open AccessHigh expression of fibroblast activation protein (FAP) predicts poor outcome in high-grade serous ovarian cancer
High-grade serous ovarian cancer (HGSOC) is a fatal form of ovarian cancer. Previous studies indicated some potential biomarkers for clinical evaluation of HGSOC prognosis. However, there is a lack of systemat...
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Article
Open AccessErythropoietin promoted the proliferation of hepatocellular carcinoma through hypoxia induced translocation of its specific receptor
Erythropoietin (EPO) is a hypoxia-inducible stimulator of erythropoiesis. Besides its traditional application in anemia therapy, it offers an effective treatment in the cancer patients, especially those who re...
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Article
Open AccessA diffusive predator-prey system with prey refuge and gestation delay
The dynamics of a diffusive predator-prey system with prey refuge and gestation delay is investigated in this paper. For a non-delay system, global stability, Turing instability and Hopf bifurcation are studie...
