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Article
Phorbol Derivatives of Croton Oil
One new seco-cyclic phorbol derivative and one new phorbol 12-monoester, named 13-oxo-14-isopropylphorbol (2), 12-angelylphorbol (5), together with four known compounds, named 4a-deoxyphorbol, 13-oxo-14-isopropen...
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Article
Open AccessA variant-proof SARS-CoV-2 vaccine targeting HR1 domain in S2 subunit of spike protein
The emerging SARS-CoV-2 variants, commonly with many mutations in S1 subunit of spike (S) protein are weakening the efficacy of the current vaccines and antibody therapeutics. This calls for the variant-proof ...
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Article
Screening for SH3TC2 variants in Charcot–Marie–Tooth disease in a cohort of Chinese patients
Mutations in the SH3TC2 gene cause Charcot–Marie–Tooth disease type 4C (CMT4C), characterized by inherited demyelinating peripheral neuropathy. CMT4C is a common form of CMT4/autosomal recessive (AR) CMT1. This s...
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Article
Diffusion-weighted MRI findings and clinical correlations in sporadic Creutzfeldt–Jakob disease
The objective of this study is to investigate the hyperintense lesions on diffusion-weighted magnetic resonance imaging (DWI) and its clinical correlation in sporadic Creutzfeldt–Jakob disease (sCJD). Patients...
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Article
The characteristics of ascites in patients with POEMS syndrome
The characteristics of ascites in patients with POEMS syndrome, which comprise polyneuropathy, organomegaly, endocrinopathy, M protein, and skin changes, are unknown. We described the frequency of ascites at p...