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Article
Helicobacter pylori HP0876 is Dispensable for Heme–Iron Acquisition but Attenuates Bacterial Adherence to Gastric Epithelial Cells
Helicobacter pylori can efficiently capture iron either from free heme or heme-containing compounds in the iron-limited gastric mucosa. However, the heme iron utilization systems of H. pylori hav...
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Article
Protection against Helicobacter pylori infection by a trivalent fusion vaccine based on a fragment of urease B-UreB414
A multivalent fusion vaccine is a promising option for protection against Helicobacter pylori infection. In this study, UreB414 was identified as an antigenic fragment of urease B subunit (UreB) and it induced an...
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Article
Fusion expression and immunogenicity of EHEC EspA-Stx2Al protein: Implications for the vaccine development
Shiga toxin 2 (Stx2) is a major virulence factor for enterohemorrhagic Escherichia coli (EHEC), which is encoded by λ lysogenic phage integrated into EHEC chromosome. Stx2Al, Al subunit of Stx2 toxin has gathered...
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Article
Proteomic Insights into Helicobacter pylori Coccoid Forms Under Oxidative Stress
Helicobacter pylori, an etiological agent of gastroduodenal diseases, undergoes drastic morphological transition from spiral shape to coccoid form under oxidative stress. However, the kno...