-
Article
Open AccessWhole‐genome sequencing identifies interferon-induced protein IFI6/IFI27-like as a strong candidate gene for VNN resistance in European sea bass
Viral nervous necrosis (VNN) is a major disease that affects European sea bass, and understanding the biological mechanisms that underlie VNN resistance is important for the welfare of farmed fish and sustaina...
-
Article
Exposure of zebrafish to an environmental mixture of persistent organic pollutants triggers an increase in anxiety-like syndrome but does not affect boldness in unexposed offspring
Polychlorinated biphenyls (PCBs) and polybrominated diphenyl ethers (PBDEs) are persistent organic pollutants (POPs) that are present as complex mixtures in all environmental compartments, including aquatic ec...
-
Chapter and Conference Paper
Insights on Ecotoxicological Effects of Microplastics in Marine Ecosystems: The EPHEMARE Project
The Ephemare project was supported in the period 2015–2018 by JPI Oceans, as one of 4 sister projects in the joint action on ecological aspects of microplastics. Ephemare investigated several issues concernin...
-
Article
Exposures of zebrafish through diet to three environmentally relevant mixtures of PAHs produce behavioral disruptions in unexposed F1 and F2 descendant
The release of polycyclic aromatic hydrocarbons (PAHs) into the environment has increased very substantially over the last decades. PAHs are hydrophobic molecules which can accumulate in high concentrations in...
-
Article
PAHs and fish—exposure monitoring and adverse effects—from molecular to individual level
-
Article
Chronic dietary exposure to pyrolytic and petrogenic mixtures of PAHs causes physiological disruption in zebrafish - part I: Survival and growth
The release of polycyclic aromatic hydrocarbons (PAHs) into the environment has increased very substantially over the last decades leading to high concentrations in sediments of contaminated areas. To evaluate...
-
Article
Chronic dietary exposure to pyrolytic and petrogenic mixtures of PAHs causes physiological disruption in zebrafish—part II: behavior
In the last 10 years, behavior assessment has been developed as an indicator of neurotoxicity and an integrated indicator of physiological disruption. Polycyclic aromatic hydrocarbon (PAH) release into the env...
-
Article
Developmental toxicity of PAH mixtures in fish early life stages. Part I: adverse effects in rainbow trout
A new gravel-contact assay using rainbow trout, Oncorhynchus mykiss, embryos was developed to assess the toxicity of polycyclic aromatic hydrocarbons (PAHs) and other hydrophobic compounds. Environmentally realis...
-
Article
Developmental toxicity of PAH mixtures in fish early life stages. Part II: adverse effects in Japanese medaka
In aquatic environments, polycyclic aromatic hydrocarbons (PAHs) mostly occur as complex mixtures, for which risk assessment remains problematic. To better understand the effects of PAH mixture toxicity on fis...
-
Article
Influence of sediment composition on PAH toxicity using zebrafish (Danio rerio) and Japanese medaka (Oryzias latipes) embryo-larval assays
Due to hydrophobic and persistent properties, polycyclic aromatic hydrocarbons (PAHs) have a high capacity to accumulate in sediment. Sediment quality criteria, for the assessment of habitat quality and risk f...
-
Article
Development of a reference artificial sediment for chemical testing adapted to the MELA sediment contact assay
Most persistent organic pollutants, due to their hydrophobic properties, accumulate in aquatic sediments and represent a high risk for sediment quality. To assess the toxicity of hydrophobic pollutants, a nove...
-
Article
Long-term disruption of growth, reproduction, and behavior after embryonic exposure of zebrafish to PAH-spiked sediment
A natural sediment spiked with three individual polycyclic aromatic hydrocarbons (PAHs; pyrene, phenanthrene and benzo[a]pyrene) was used to expose zebrafish embryos and larvae during 4 days. The total PAH concen...
-
Article
Open AccessDe novo assembly, characterization and functional annotation of Senegalese sole (Solea senegalensis) and common sole (Solea solea) transcriptomes: integration in a database and design of a microarray
Senegalese sole (Solea senegalensis) and common sole (S. solea) are two economically and evolutionary important flatfish species both in fisheries and aquaculture. Although some genomic resources and tools were r...
-
Article
Acetylcholinesterase is required for neuronal and muscular development in the zebrafish embryo
The neurotransmitter acetylcholine (ACh) has a crucial role in central and neuromuscular synapses of the cholinergic system. After release into the synaptic cleft, ACh is rapidly degraded by acetylcholinestera...
-
Chapter
Identification of Residues Involved in Naja Naja Oxiana AChE Insensitivity to Fasciculin
AChEs from Elapid venoms have been recently characterized in detail, they present several specific properties when compared to other vertebrates enzymes. Venom AChEs are monomers and their sensitivity to fascicul...
-
Chapter
ESTHER 1998, aChEdb Short Tutorial
ESTHER (for esterases, a/b hydrolase enzyme and relatives) is a database aimed at collecting in one information system, sequence data together with annotations. These include experimental biochemical results rela...
-
Chapter
Acetylcholinesterase in Elapid Snakes
Acetylcholinesterase (AChE) plays a key role in cholinergic transmission, but is also present in non-cholinergic contexts where its function is not clearly known (1). This is the case in pulmonary and intestin...
-
Chapter
Acetylcholinesterase Expression During Development of Danio Rerio
Numerous observations suggest a “non classical” role for acetylcholinesterase during development (1). We are interested in testing this hypothesis during early development of the teleost Danio rerio (zebrafish).
-
Chapter
Properties of Class a Acetylcholinesterase, the Enzyme Encoded by ACE-1 in Caenorhabditis elegans
Three genes (ace-1, ace-2, and ace-3) encode acetylcholinesterases (AChEs) in the nematode Caenorhabditis elegans (review in Johnson, 1991). The three enzymes differ in their catalytic properties and are called A...
