74 Result(s)

Article

Early death in acute promyelocytic leukemia (APL) in French centers: a multicenter study in 399 patients

R Rahmé, X Thomas, C Recher, N Vey, J Delaunay, E Deconinck, P Hirsch… in Leukemia (2014)

Article

Impact of raw pig slurry and pig farming practices on physicochemical parameters and on atmospheric N₂O and CH₄ emissions of tropical soils, Uvéa Island (South Pacific)

Emissions of CH₄ and N₂O related to private pig farming under a tropical climate in Uvéa Island were studied in this paper. Physicochemical soil parameters such as nitrate, nitrite, ammonium, Kjeldahl nitrogen, t...

E. Roth, P. Gunkel-Grillon, L. Joly… in Environmental Science and Pollution Resear… (2014)

Article

High burden of BK virus-associated hemorrhagic cystitis in patients undergoing allogeneic hematopoietic stem cell transplantation

BK virus (BKV) reactivation has been increasingly associated with the occurrence of late-onset hemorrhagic cystitis (HC) after allogeneic hematopoietic SCT (allo-HSCT) resulting in morbidity and sometimes mort...

L Gilis, S Morisset, G Billaud, S Ducastelle-Leprêtre… in Bone Marrow Transplantation (2014)

Article

Evaluation of allogeneic hematopoietic SCT in younger adults with adverse karyotype AML

To illustrate methodological issues, we compared donor vs no-donor to transplant vs no-transplant comparisons in a cohort of 107 patients aged ⩽50 years with adverse karyotype AML in first CR. Adverse karyotyp...

M A Hospital, X Thomas, S Castaigne, E Raffoux, C Pautas… in Bone Marrow Transplantation (2012)

Article

Invasive aspergillosis: an important risk factor on the short- and long-term survival of acute myeloid leukemia (AML) patients

Invasive aspergillosis (IA) during induction chemotherapy of acute myeloid leukemia (AML) could worsen the prognosis. Our objective was to study how the development of IA during AML interferes with the therape...

M. Michallet, T. Bénet, M. Sobh, S. Kraghel… in European Journal of Clinical Microbiology … (2012)

Article

Prognostic significance of DNA methyltransferase 3A mutations in cytogenetically normal acute myeloid leukemia: a study by the Acute Leukemia French Association

Recently, DNA methyltransferase 3A (DNMT3A) mutations have been identified in acute myeloid leukemia (AML), the highest frequency being found within cytogenetically normal (CN) AML. In this study, diagnostic samp...

A Renneville, N Boissel, O Nibourel, C Berthon, N Helevaut, C Gardin… in Leukemia (2012)

Article

Wilms' tumor 1 single-nucleotide polymorphism rs16754 does not predict clinical outcome in adult acute myeloid leukemia

A Renneville, N Boissel, N Helevaut, O Nibourel, C Terré, C Pautas, C Gardin… in Leukemia (2011)

Article

Development of a versatile atmospheric N₂O sensor based on quantum cascade laser technology at 4.5 μm

We report the development of a field-deployable infrared laser spectrometer using new quantum cascade laser technology at 4.5 μm. The instrument is designed to measure in situ N₂O concentrations at ground level e...

L. Joly, T. Decarpenterie, N. Dumelié, X. Thomas, I. Mappe-Fogaing… in Applied Physics B (2011)

Article

Another pedigree with familial acute myeloid leukemia and germline CEBPA mutation

A Renneville, V Mialou, N Philippe, S Kagialis-Girard, V Biggio, M-T Zabot… in Leukemia (2009)

Article

Is there a role for all-trans retinoic acid in combination with recombinant erythropoetin in myelodysplastic syndromes? A report on 59 cases

Erythropoiesis-stimulating agents (ESAs) remain the first-line treatment of anemia in lower risk myelodysplastic syndromes (MDS) without 5q deletion. A preliminary report suggested that adding all-trans retinoic ...

R Itzykson, S Ayari, D Vassilief, E Berger, B Slama, N Vey, F Suarez… in Leukemia (2009)

Article

Recurrent in-frame insertion in C/EBPα TAD2 region is a polymorphism without prognostic value in AML

V Biggio, A Renneville, O Nibourel, N Philippe, L Terriou, C Roumier, P Amouyel… in Leukemia (2008)

Article

Outcome of treatment after first relapse in adults with acute lymphoblastic leukemia initially treated by the LALA-94 trial

Fifty-four percent of adults with acute lymphoblastic leukemia (ALL) who entered the LALA-94 trial experienced a first relapse. We examined the outcome of these 421 adult patients. One hundred and eighty-seven...

E Tavernier, J-M Boiron, F Huguet, K Bradstock, N Vey, T Kovacsovics… in Leukemia (2007)

Article

Effect of priming with granulocyte–macrophage colony-stimulating factor in younger adults with newly diagnosed acute myeloid leukemia: a trial by the Acute Leukemia French Association (ALFA) Group

In a multicenter trial, 259 young adults (15–49 years) with newly diagnosed acute myeloid leukemia (AML) were first randomized to receive a timed-sequential induction regimen given either alone (135 patients) ...

X Thomas, E Raffoux, S de Botton, C Pautas, P Arnaud, T de Revel, O Reman… in Leukemia (2007)

Article

High efficacy and safety profile of fractionated doses of Mylotarg as induction therapy in patients with relapsed acute myeloblastic leukemia: a prospective study of the alfa group

Pivotal phase II studies in acute myeloblastic leukemia (AML) patients in first relapse have used gemtuzumab ozogamicin (GO) (Mylotarg) at a dose of 9 mg/m² on days 1 and 14. These studies showed a 26% response r...

A-L Taksin, O Legrand, E Raffoux, T de Revel, X Thomas, N Contentin… in Leukemia (2007)

Article

Prospective multicentric molecular study for poor prognosis fusion transcripts at diagnosis in adult B-lineage ALL patients: the LALA 94 experience

C Picard, S Hayette, C Bilhou-Nabera, J M Cayuela, E Delabesse, N Frenoy… in Leukemia (2006)

Article

Allogeneic stem cell transplantation improves the outcome of adults with t(1;19)/E2A-PBX1 and t(4;11)/MLL-AF4 positive B-cell acute lymphoblastic leukemia: results of the prospective multicenter LALA-94 study

Adult patients with acute lymphoblastic leukemia (ALL) and t(1;19)/E2A-PBX1 or t(4;11)/MLL-AF4 have a poor outcome. We have evaluated the impact of an intensified post-remission therapy using a high-dose chemothe...

N Vey, X Thomas, C Picard, T Kovascovicz, C Charin, J M Cayuela, H Dombret… in Leukemia (2006)

Article

Alloreaction increases or restores CD40, CD54, and/or HLA molecule expression in acute myelogenous leukemia blasts, through secretion of inflammatory cytokines: dominant role for TNFβ, in concert with IFNγ

We have previously reported that alloreaction can lead to activation of dendritic cells through secretion of inflammatory cytokines. Here, we addressed whether alloreaction-derived cytokines may also lead to a...

A Eljaafari, J Van Snick, A Voisin, F Cormont, A Farre, J Bienvenu, J Bernaud… in Leukemia (2006)

Article

Non-infusional vs intravenous consolidation chemotherapy in elderly patients with acute myeloid leukemia: final results of the EORTC-GIMEMA AML-13 randomized phase III trial

In this trial, acute myeloid leukemia patients (pts) aged 61–80 years received MICE (mitoxantrone, etoposide and cytarabine) induction chemotherapy in combination with different schedules of granulocyte colony...

U Jehn, S Suciu, X Thomas, F Lefrère, P Muus, Z Berneman, J-P Marie, F Adamo… in Leukemia (2006)