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  1. No Access

    Chapter

    Natural Products for the Management of Asthma and COPD

    Chronic airway inflammatory diseases like asthma, chronic obstructive pulmonary disease (COPD), and their associated exacerbations cause significant socioeconomic burden. There are still major obstacles to eff...

    Wupeng Liao, Quy T. N. Tran, Hong Yong Peh, Christabel Clare M. Y. Chan… (2024)

  2. Article

    Open Access

    Isthmin-1 attenuates allergic Asthma by stimulating adiponectin expression and alveolar macrophage efferocytosis in mice

    Allergic asthma is a common respiratory disease that significantly impacts human health. Through in silico analysis of human lung RNASeq, we found that asthmatic lungs display lower levels of Isthmin-1 (ISM1) ...

    Jong Huat Tee, Udhaya Vijayakumar, Mahalakshmi Shanmugasundaram… in Respiratory Research (2023)

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  3. Article

    Open Access

    ISM1 suppresses LPS-induced acute lung injury and post-injury lung fibrosis in mice

    Acute lung injury/acute respiratory distress syndrome (ALI/ARDS) are clinical syndromes characterized by acute lung inflammation, pulmonary edema and hypoxemia, with up to 50% mortality rate without effective ...

    Ngan Nguyen, Simin Xu, Terence Yin Weng Lam, Wupeng Liao… in Molecular Medicine (2022)

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