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  1. Article

    Open Access

    Conversion surgery for advanced hepatocellular carcinoma after combination treatment of lenvatinib and camrelizumab: a case report

    Hepatocellular carcinoma (HCC) is an aggressive malignancy with high morbidity and mortality. Conversion therapy can improve surgical resection rate and prolong survival time for patients with advanced HCC. We...

    Zhihong Chen, Zhenrong Chen, Wu Fan, Yi** Zou… in World Journal of Surgical Oncology (2023)

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  2. Article

    Open Access

    Untargeted metabolomics reveals the effect of lovastatin on steroid-induced necrosis of the femoral head in rabbits

    Lovastatin is an important medicine and it shows a significant effect against glucocorticoid-induced necrosis of the femoral head. This study aimed to investigate the effect of lovastatin on preventing necrosi...

    **angnan Ren, Zixing Shao, Wu Fan… in Journal of Orthopaedic Surgery and Research (2020)

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  3. No Access

    Article

    4-phenylbutyric acid attenuates endoplasmic reticulum stress-mediated apoptosis and protects the hepatocytes from intermittent hypoxia-induced injury

    To investigate the effect of 4-phenylbutyric acid (4-PBA) on intermittent hypoxia (IH)-induced liver cell injury and to clarify the underlying mechanisms.

    Liu **n, Wu Fan, Du Tingting, Sun Zuoming, Zhang Qiang in Sleep and Breathing (2019)

  4. No Access

    Article

    Effects of oxidized low density lipoprotein on the expression and function of ABCA1 in macrophages

    In the present study, we examined the regulation of the expression and function of ABCA1 by modified LDL (ox-LDL)in vitro. After incubation with apoA-I for 24 h, RAW264. 7 cells effluxed 37.65% cholesterol loaded...

    Li Yinghon, Bi Hao, Wu Fan, Zong Yiqiang, Wang Yan, Qu Shen in Current Medical Science (2005)

  5. No Access

    Article

    β-VLDL induced VLDL-R’s up-regulation via PKC-ERK1/2 signal pathway

    To explore the intracellular signal pathways for β-VLDL induced very low density lipoprotein receptor (VLDL-R) transcription up-regulation and their effects on lipid accumulation in macrophages, Western Blot w...

    Liu Zhiguo, Wang Yan, Qu Shen, Feng Youmei, Wu Fan, Zong Yiqiang… in Current Medical Science (2004)

  6. No Access

    Article

    Treatment of menopausal syndrome by acupuncture: A report of 38 cases

    To observe the acupuncture treatment of 38 patients with menopausal syndrome. The main acupoints were Fengchi (GB 20), Taiyang (Ex-HN5), Hegu (LI 4), Neiguan (PC 6), Qihai (CV 6), Yanglingquan (GB 34), Taichon...

    Guan Jian-hong, Ma Feng-sheng, Wu Fan… in Journal of Acupuncture and Tuina Science (2004)

  7. No Access

    Article

    Preparation and characterization of polyclonal antibodies against VLDL receptor

    The polyclonal antibodies against VLDL receptor were prepared and identified. Rabbits were immunized with polypeptide fragment of VLDL receptor as antigen. The collected blood serum of the immunized rabbits wa...

    Qu Shen, Chen Tao, Wu Fan, Yin Yanhua, Bi Hao in Current Medical Science (2004)

  8. No Access

    Article

    Role of VLDL receptor in the process of foam cell formation

    The role of very low density lipoprotein receptor (LVLDR) in the process of foam cell formation was investigated. After the primary cultured mouse peritoneal macrophages were incubated with VLDL, β-VLDL or low...

    Qu Shen, Wu Fan, Tian Jun, Li Yinghong, Wang Yan, Wang Yuzhe… in Current Medical Science (2004)

  9. No Access

    Article

    Induction of very low density lipoprotein receptor (VLDLR) transcription by VLDL is mediated by the extracellular signal-regulated kinase signaling pathway

    To elucidate the intracellular signaling pathways for VLDL-induced VLDLR transcription, Western blot analysis was used to examine phosphorylated ERK1/2 protein. It was found that that VLDL induced an increase ...

    Wang Yan, Qu Shen, Zong Yiqiang, Zhang Mingtao, Wu Fan in Current Medical Science (2003)