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  1. No Access

    Article

    Water-Soluble Se-Containing Proteins from Chicken Alleviate DSS-Induced Ulcerative Colitis in Mice via Inhibiting TLR4/MyD88 Pathway and Protecting the Goblet Cell Pathway

    The influence of water-soluble selenium-containing proteins (WSSeP) in chicken on ulcerative colitis (UC) is not known. This work aims to investigate the effect of two WSSeP including h-Se with 1.78 μg Se/g an...

    Yuancheng Li, Yanlong Xu, **n Hu, Chenxi Li, Lulu Wei… in Biological Trace Element Research (2024)

  2. No Access

    Article

    Gut Microbiota-Mediated Alterations of Hippocampal CB1R Regulating the Diurnal Variation of Cognitive Impairment Induced by Hepatic Ischemia–Reperfusion Injury in Mice

    Patients suffering from hepatic ischemia–reperfusion injury (HIRI) frequently exhibit postoperative cognitive deficits. Our previous observations have emphasized the diurnal variation in hepatic ischemia–reper...

    Zhigang He, Yanbo Liu, Zhen Li, Tianning Sun, Zhixiao Li… in Neurochemical Research (2024)

  3. No Access

    Article

    The Relationship Between Heavy Metals and Missed Abortion: Using Mediation of Serum Hormones

    Accumulating evidence suggests that heavy metal exposure may have adverse effects on the fetal development. Furthermore, disruption of serum hormone homeostasis can result in the adverse pregnancy outcomes. Th...

    Haixia Liu, Zhilan Li, Li’ao **e, Guangzhuang **g… in Biological Trace Element Research (2024)

  4. No Access

    Article

    Activation of Ventral Tegmental Area Dopaminergic Neurons Projecting to the Parabrachial Nucleus Promotes Emergence from Propofol Anesthesia in Male Rats

    Since the clinical introduction of general anesthesia, its underlying mechanisms have not been fully elucidated. The ventral tegmental area (VTA) and parabrachial nucleus (PBN) play pivotal roles in the mechan...

    Lei Jia, Jieting Yin, Tielong Liu, Wenqiang Qi, Tongyu Du… in Neurochemical Research (2024)

  5. Article

    Open Access

    GDPD3 Deficiency Alleviates Neuropathic Pain and Reprograms Macrophagic Polarization Through PGE2 and PPARγ Pathway

    The complex mechanism of neuropathic pain involves various aspects of both central and peripheral pain conduction pathways. An effective cure for neuropathic pain therefore remains elusive. We found that defic...

    Wenqian Li, Youjia Fan, Haizhen Lan, **aoxiao Li, Qichao Wu… in Neurochemical Research (2024)

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  6. Article

    Correction to: Knock‑Down of CD24 in Astrocytes Aggravates Oxyhemoglobin‑Induced Hippocampal Neuron Impairment

    **ang‑**n Chen, Tao Tao, Sen Gao, Han Wang, **ao‑Ming Zhou… in Neurochemical Research (2024)

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  7. No Access

    Article

    Morphine Induced Neuroprotection in Ischemic Stroke by Activating Autophagy Via mTOR-Independent Activation of the JNK1/2 Pathway

    Morphine (Mor) has exhibited efficacy in safeguarding neurons against ischemic injuries by simulating ischemic/hypoxic preconditioning (I/HPC). Concurrently, autophagy plays a pivotal role in neuronal survival...

    Wenying Chi, Yaru Huang, Peilong Li, **a Wang, Junfa Li… in Neurochemical Research (2024)

  8. No Access

    Article

    Combination of Selenite and Butyrate Enhances Efficacy Against Colon Cancer by Targeting ASCT2-Mediated Amino Acid Metabolism

    Drug combination is considered to be an effective approach to improve the efficacy of cancer therapy and chemoprevention. Selenite, a representative of inorganic form of selenium, and butyrate, a major short-c...

    **ling Cui, **gsi Li, Shuang Zhao, Lihong Fan… in Biological Trace Element Research (2024)

  9. No Access

    Article

    METTL3-modified lncRNA DSCAM-AS1 promotes breast cancer progression through inhibiting ferroptosis

    Numerous studies have indicated that N6-methyladenosine (m6A) and lncRNAs play pivotal roles in human cancer. However, the underlying functions and mechanisms of m6A-lncRNA in the physiological processes of breas...

    Zeming Yan, Zhongzeng Liang, Kangwei Luo… in Journal of Bioenergetics and Biomembranes (2024)

  10. No Access

    Article

    miR-221-3p is upregulated in acute pulmonary embolism complicated with pulmonary hypertension and promotes pulmonary arterial smooth muscle cells proliferation and migration by inhibiting PTEN

    Pulmonary arterial smooth muscle cells (PASMCs) functions are associated with the pathogenesis of pulmonary hypertension (PH) which is a life-threatening complication of acute pulmonary embolism (APE). This st...

    Lei Tang, Shuai Niu, **wei Xu, Wei Lu, Li Zhou in Cytotechnology (2024)

  11. No Access

    Article

    The Role of Histone H2B Acetylation Modification in Aluminum-Induced Cognitive Dysfunction

    Aluminum (Al) is a low toxic trace element that can accumulate in the nervous system and induce cognitive disorders characterized by reduced learning and memory ability. Neuroepigenetic effects are structural ...

    Jie Gao, Wei Liu, **g Pei, **g Li, Ni** Hao… in Biological Trace Element Research (2024)

  12. No Access

    Article

    Phosphodiesterase 8 (PDE8): Distribution and Cellular Expression and Association with Alzheimer’s Disease

    Phosphodiesterase 8 (PDE8), as a member of PDE superfamily, specifically promotes the hydrolysis and degradation of intracellular cyclic adenosine monophosphate (cAMP), which may be associated with pathogenesi...

    Nian-zhuang Qiu, Hui-mei Hou, Tian-yang Guo, Yu-li Lv, Yao zhou… in Neurochemical Research (2024)

  13. No Access

    Article

    Schwann Cell-Derived Exosomes Induced Axon Growth after Spinal Cord Injury by Decreasing PTP-σ Activation on CSPGs via the Rho/ROCK Pathway

    Spinal cord injury (SCI) is a severe neurological condition that involves a lengthy pathological process. This process leads to the upregulation of chondroitin sulfate proteoglycans (CSPGs) by reactive glia, w...

    Shibo Zhu, Hongpeng Ma, Mengfan Hou, Hailiang Li, Guangzhi Ning in Neurochemical Research (2024)

  14. No Access

    Article

    Raddeanin A Protects the BRB Through Inhibiting Inflammation and Apoptosis in the Retina of Alzheimer’s Disease

    Neuroinflammation and endothelial cell apoptosis are prominent features of blood–brain barrier (BBB) disruption, which have been described in Alzheimer’s disease (AD) and can predict cognitive decline. Recent ...

    **ao-Fang Wang, **ao-Hong **ang, **g Wei, Peng-Bo Zhang, Qin Xu… in Neurochemical Research (2024)

  15. No Access

    Article

    Association Between Multiple Metal(loid)s Exposure and Blood Lipid Levels: Evidence from a Cross-Sectional Study of Southeastern China

    Exposure to essential and toxic metals occurs simultaneously as a mixture in real-life. However, there is no consensus regarding the effects of co-exposure to multiple metal(loid)s (designated hereafter metals...

    Guihua Du, **aoguang Song, Fankun Zhou, Lu Ouyang… in Biological Trace Element Research (2024)

  16. No Access

    Article

    miR-206-3p Targets Brain-Derived Neurotrophic Factor and Affects Postoperative Cognitive Function in Aged Mice

    Postoperative cognitive dysfunction (POCD) occurs after surgery and severely impairs patients’ quality of life. Finding POCD-associated variables can aid in its diagnosis and prognostication. POCD is associate...

    Shentong Wang, Jia Zhao, Chengran Wang, Yuhan Yao, Zhiyao Song… in Neurochemical Research (2024)

  17. No Access

    Article

    AdipoRon Ameliorates Synaptic Dysfunction and Inhibits tau Hyperphosphorylation through the AdipoR/AMPK/mTOR Pathway in T2DM Mice

    There is growing evidence showing that adiponectin (APN) can improve Alzheimer’s disease(AD)-like pathological changes by improving insulin resistance. However, the role of AdipoRon (an Adiponectin receptor ag...

    Wenyan Zhao, Wei Zhang, Yingying Hu, Yuliang Zhou, **ying Zhao… in Neurochemical Research (2024)

  18. No Access

    Article

    Comprehensive Insights into the Health Effects of Selenium Exposure and Supplementation Among the Chinese Community Middle-Aged and Elderly: a Combined Retrospective Cohort Study and Intervention Study

    Selenium (Se) is an essential trace element for maintaining human health, for example, plays a crucial role in preventing aging-related diseases. However, most studies on the health effects of Se among the com...

    Chen Li, **angwen Peng, Jiayang Zheng, Kexin Shi… in Biological Trace Element Research (2024)

  19. No Access

    Article

    The modification of heme special importer to improve the production of active hemoglobins in Escherichia coli

    To enhance the import of heme for the production of active hemoproteins in Escherichia coli C41 (DE3) lacking the special heme import system, heme receptor ChuA from E. coli Nissle 1917 was modified through molec...

    Zihan Zhang, Baodong Hu, Tao Zhang, Zhengshan Luo, **gwen Zhou… in Biotechnology Letters (2024)

  20. No Access

    Article

    Effects of miR-204-5p and Target Gene EphB2 on Cognitive Impairment Induced by Aluminum Exposure in Rats

    Aluminum is a common environmental neurotoxin. Aluminum ions can cross the blood–brain barrier and accumulate in different brain regions, damage brain tissue, and cause cognitive impairment, but the molecular ...

    Wei Liu, Jie Gao, Ni** Hao, **g Li, **g Pei… in Biological Trace Element Research (2024)

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