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Article
Open AccessMetal organic framework-coated gold nanorod as an on-demand drug delivery platform for chemo-photothermal cancer therapy
Chemo-photothermal therapy based on nanoparticles has emerged as a promising strategy for cancer treatment. However, its therapeutic efficacy and application potential are largely subjected to the uncontrollab...
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Article
Rapid hybrid microwave cladding of SiO2/TiO2 sol–gel derived composite coatings
UV protection and coatings for plastics are important in many applications. The cladding of low microwave (MW) absorption composite coatings on high MW transparent plastic substrates is a challenge due to thei...
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Article
Finite element simulation of hybrid microwave sintering based on power approach
Microwave (MW) sintering offers higher heating rate, rapid processing, reduced energy consumption, and reduced sintering temperature. However, the technique is not fully understood, difficult to control, and o...
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Article
Aggregation-induced emission (AIE) dye loaded polymer nanoparticles for gene silencing in pancreatic cancer and their in vitro and in vivo biocompatibility evaluation
We have developed aggregation-induced emission (AIE) dye loaded polymer nanoparticles with deep-red emission for siRNA delivery to pancreatic cancer cells. Two US Food and Drug Administration (FDA) approved su...
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Article
Plasmonic Semiconductor Nanocrystals as Chemical Sensors: Pb2+ Quantitation via Aggregation-Induced Plasmon Resonance Shift
We demonstrate, for the first time, the use of plasmonic semiconductor nanocrystals for the analysis of heavy metal ions in water. This highly sensitive localized surface plasmon resonance (LSPR)-based platfor...
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Article
Functionalized Plasmonic Anisotropic Nanocrystals for Multimodal Imaging of Cancer Cells
Nanoparticles internalized by cells are valuable probes for bioimaging. In particular, nanoparticles can be detected in “biological transmission window,” i.e., near infrared region. Here, we report a preparati...
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Article
Nanoparticle Based Galectin-1 Gene Silencing, Implications in Methamphetamine Regulation of HIV-1 Infection in Monocyte Derived Macrophages
Galectin-1, an adhesion molecule, is expressed in macrophages and implicated in human immunodeficiency virus (HIV-1) viral adsorption. In this study, we investigated the effects of methamphetamine on galectin-...
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Article
A pilot study in non-human primates shows no adverse response to intravenous injection of quantum dots
Quantum dots have been used in biomedical research for imaging1,2, diagnostics3,4 and sensing purposes5,6. However, concerns over the cytotoxicity of their heavy metal constituents7,8 and conflicting results from...
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Article
Fluorescence Imaging of the Lymph Node Uptake of Proteins in Mice after Subcutaneous Injection: Molecular Weight Dependence
To use noninvasive fluorescence imaging to investigate the influence of molecular weight (MW) of proteins on the rate of loss from a subcutaneous (SC) injection site and subsequent uptake by the draining lymph...
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Article
Open AccessQuantum dot-doped porous silicon metal–semiconductor metal photodetector
In this paper, we report on the enhancement of spectral photoresponsivity of porous silicon metal–semiconductor metal (PS-MSM) photodetector embedded with colloidal quantum dots (QDs) inside the pore layer. Th...
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Article
Application of Gold Nanorods for Plasmonic and Magnetic Imaging of Cancer Cells
We report the use of biocompatible gold nanorods (GNRs) as multimodal (plasmonic and magnetic) probes for cancer cell labeling in vitro. These multifunctional and multimodal bioconjugates were prepared by repl...
