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    Article

    In vivo conversion of astrocytes to neurons in the injured adult spinal cord

    Spinal cord injury (SCI) leads to irreversible neuronal loss and glial scar formation, which ultimately result in persistent neurological dysfunction. Cellular regeneration could be an ideal approach to replen...

    Zhida Su, Wenze Niu, Meng-Lu Liu, Yuhua Zou, Chun-Li Zhang in Nature Communications (2014)

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    In vivo reprogramming of astrocytes to neuroblasts in the adult brain

    Adult differentiated cells can be reprogrammed into pluripotent stem cells or lineage-restricted proliferating precursors in culture; however, this has not been demonstrated in vivo. Here, we show that the single...

    Wenze Niu, Tong Zang, Yuhua Zou, Sanhua Fang, Derek K. Smith in Nature Cell Biology (2013)