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Article
In vivo conversion of astrocytes to neurons in the injured adult spinal cord
Spinal cord injury (SCI) leads to irreversible neuronal loss and glial scar formation, which ultimately result in persistent neurological dysfunction. Cellular regeneration could be an ideal approach to replen...
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Article
In vivo reprogramming of astrocytes to neuroblasts in the adult brain
Adult differentiated cells can be reprogrammed into pluripotent stem cells or lineage-restricted proliferating precursors in culture; however, this has not been demonstrated in vivo. Here, we show that the single...