55 Result(s)

Article

Prediction of lymph node metastasis in T1 colorectal cancer based on combination of body composition and vascular invasion

Lymph node metastasis (LNM) in colorectal cancer (CRC) patients is not only associated with the tumor’s local pathological characteristics but also with systemic factors. This study aims to assess the feasibil...

Shizhen Zhou, Qinggang Yuan, Lixiang Liu… in International Journal of Colorectal Disease (2024)

Article

Clinical characteristics and prognostic analysis of postoperative recurrence or metastasis of low-risk gastrointestinal stromal tumors

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the digestive tract. This study aimed to investigate the clinical characteristics and prognosis of postoperative recurrence or ...

Lianlian Cao, Chen Lin, Yu Liu, Chao Sui, Zhao** Li… in World Journal of Surgical Oncology (2024)

Article

CHEK2 knockout is a therapeutic target for TP53-mutated hepatocellular carcinoma

Currently, there is still a lack of novel and effective drug targets to improve the prognosis of hepatocellular carcinoma (HCC). Additionally, the role of CHEK2 in HCC has not been reported yet. The eQTLgen da...

Yuyan Chen, Zhengyi Zhu, **ngyu Wu, Hui Li, Wenxian Guan… in Cell Death Discovery (2024)

Article

Umbrella strategy with systemic and intraperitoneal chemotherapy versus systemic chemotherapy in patients with advanced gastric cancer: a multicenter, randomized Phase III clinical trial

We have developed a tridirectional regimen combining intraperitoneal, intravenous, and oral chemotherapy as a treatment for patients with advanced gastric cancer and individualized these chemotherapeutics acco...

Yang Yang, Jia Wei, Juan Du, Zhengyun Zou, Rongfu Wei… in Clinical Cancer Bulletin (2023)

Article

Risk factors of additional surgery after non-curative endoscopic submucosal dissection for early gastric cancer

The criteria for surgical intervention after non-curative endoscopic submucosal dissection (ESD) of early gastric cancer are unclear. We aimed to clarify the risk factors for residual cancer and lymph node met...

Feng Sun, Yibo Huang, Yan Sun, **ngzhou Wang, Shichao Ai… in BMC Gastroenterology (2023)

Article

Dual tracer navigation for lymph node dissection in laparoscopic radical gastrectomy (DANCE trial): a protocol for a prospective, randomized clinical trial

Lymph node (LN) metastasis is the most common metastasis route in gastric cancer. Extensive dissection of LNs can significantly improve the prognosis of patients with gastric cancer. Recently, multiple clinica...

Yanjun Lu, Shichao Ai, Peng Song, Yan Sun, **aofei Shen, Feng Sun, Qiongyuan Hu… in Trials (2023)

Article

Neoadjuvant sintilimab in combination with concurrent chemoradiotherapy for locally advanced gastric or gastroesophageal junction adenocarcinoma: a single-arm phase 2 trial

In this multicenter, single-arm phase 2 trial (ChiCTR1900024428), patients with locally advanced gastric/gastroesophageal junction cancers receive one cycle of sintilimab (anti-PD1) and chemotherapy (S-1 and n...

Jia Wei, **aofeng Lu, Qin Liu, Yao Fu, Song Liu, Yang Zhao… in Nature Communications (2023)

Article

Prognostic analysis of 2–5 cm diameter gastric stromal tumors with exogenous or endogenous growth

There has been limited research on the prognosis differences in patients with gastric stromal tumor invasion of the plasma membrane surface. This study intended to investigate whether there is a difference in ...

Chen Lin, Chao Sui, Tingting Tao, Wenxian Guan… in World Journal of Surgical Oncology (2023)

Article

Correction to: Prognostic significance of serum CA125 in the overall management for patients with gastrointestinal stromal tumors

Chao Sui, Chen Lin, Tingting Tao, Wenxian Guan, Haoran Zhang… in BMC Gastroenterology (2023)

Article

Prognostic significance of serum CA125 in the overall management for patients with gastrointestinal stromal tumors

Carbohydrate antigen 125 (CA125) is elevated as a tumor marker in many carcinomas, but its association with gastrointestinal stromal tumor (GIST) has received less attention. This study intends to evaluate whe...

Chao Sui, Chen Lin, Tingting Tao, Wenxian Guan, Haoran Zhang… in BMC Gastroenterology (2023)

Article

Oxygen tank for synergistic hypoxia relief to enhance mitochondria-targeted photodynamic therapy

Mitochondria play an essential role in cellular redox homeostasis maintenance and meanwhile serve as an important target for organelle targeted therapy. Photodynamic therapy (PDT) is a promising strategy for o...

**anghui Li, Haoran Wang, Zhiyan Li, Dandan Li, **aofeng Lu… in Biomaterials Research (2022)

Article

Comparison of short-term outcomes between robotic-assisted and laparoscopic gastrectomy guided by carbon nanoparticle suspension injection in gastric cancer

The clinical application of robotic-assisted gastrectomy remains controversial, especially as clinical studies of this operation navigated by carbon nanoparticle suspension injection (CNSI) have not been condu...

Zhiyan Li, Shichao Ai, Feng Wang, Liang Tao, Feng Sun… in World Journal of Surgical Oncology (2022)

Article

Correction to: Associations between nutrition risk scores and sarcopenia in gastrointestinal cancer patients: a cross‑sectional study

Bo Gao, Wenqing Chen, Yu Liu, Yuan Li, **angrui Li, Chao Ding… in Supportive Care in Cancer (2022)

Article

The miR-532-E2F1 feedback loop contributes to gastric cancer progression

Gastric cancer (GC) ranks fourth in incidence and mortality worldwide, ascertaining the pathogenesis of GC is crucial for its treatment. E2F1, which regulates the transcription of genes encoding proteins invol...

Shanting Gao, **aomin Bu, Yongyue Gao, Zengtao Bao, Wenchao Shi… in Cell Death & Disease (2022)

Article

Correction to: Anoikis resistant gastric cancer cells promote angiogenesis and peritoneal metastasis through C/EBPβ-mediated PDGFB autocrine and paracrine signaling

Shangce Du, Zhi Yang, **aofeng Lu, Suhail Yousuf, Min Zhao, Wenxi Li, Ji Miao… in Oncogene (2022)

Article

Correction to: Tenascin-c knockdown suppresses vasculogenic mimicry of gastric cancer by inhibiting ERK- triggered EMT

**ng Kang, En Xu, **ngzhou Wang, Lulu Qian, Zhi Yang, Heng Yu… in Cell Death & Disease (2021)

Article

Tenascin-c knockdown suppresses vasculogenic mimicry of gastric cancer by inhibiting ERK- triggered EMT

Gastric cancer is one of the most common malignancies worldwide and vasculogenic mimicry (VM) is considered to be the leading cause for the failure of anti-angiogenesis therapy in advanced gastric cancer patie...

**ng Kang, En Xu, **ngzhou Wang, Lulu Qian, Zhi Yang, Heng Yu… in Cell Death & Disease (2021)

Article

Author Correction: miR-93 functions as an oncomiR for the downregulation of PDCD4 in gastric carcinoma

Hongwei Liang, Feng Wang, Dan** Chu, Weijie Zhang, Zhicong Liao… in Scientific Reports (2021)