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  1. Article

    Open Access

    Iruplinalkib (WX‑0593), a novel ALK/ROS1 inhibitor, overcomes crizotinib resistance in preclinical models for non-small cell lung cancer

    Despite remarkable initial responses of anaplastic lymphoma kinase (ALK) inhibitors in ALK-positive non-small cell lung cancer (NSCLC) patients, cancers eventually develop resistance within one to two years. This...

    Yingying Yang, Qingmei Zheng, **nmei Wang, Shuyong Zhao in Investigational New Drugs (2023)

  2. No Access

    Article

    Transcriptome Analysis of the Digestive Tract of Tachypleus tridentatus and Carcinoscorpius rotundicauda

    Transcriptome assemblies for the stomach, midgut, and fecal mucosa of Tachypleus tridentatus and Carcinoscorpius rotundicauda are reported for the first time in this study. Genome assembly resulted in 373069 unig...

    Yuhong Li, Kit Yue Kwan, Sansu Li, Yingchun Liu in Journal of Ocean University of China (2022)

  3. Article

    Open Access

    Proteomic analyses on the browning of shade-dried Thompson seedless grape

    China is one of the main producers in the worldwide raisin market. Most China’s raisins are produced in **njiang where the Thompson seedless grape (Vitis vinifera L.cv.Thompson seedless) is the main variety of gr...

    Fengjuan Liu, Wenshu Huang, Zuoshan Feng, Yongxia Tao in Applied Biological Chemistry (2021)

  4. No Access

    Article

    Differential protein expression profiling in Pleurotus ferulae mycelium caused by asafoetida extracts using a proteomics approach

    The precise mechanism by which asafoetida extract influenced the growth of Pleurotus ferulae mycelium was investigated using a comparative proteomic analysis approach. Two types of asafoetida extracts were added ...

    Yujia Bai, Wenshu Huang, Yongxia Tao in Journal of the Korean Society for Applied … (2014)

  5. No Access

    Article

    Isolation and Identification of a Novel Inducible Antibacterial Peptide from the Skin Mucus of Japanese Eel, Anguilla japonica

    In this study, acetone extracts and acidic extracts were prepared from skin mucus, gill, kidney, liver and spleen of the Japanese eel, Anguilla japonica, and they exhibited different levels of antibacterial activ...

    Ying Liang, Ruizhang Guan, Wenshu Huang, Tongling Xu in The Protein Journal (2011)

  6. No Access

    Article

    Two copies of the genes encoding the subunits of putative interleukin (IL)-4/IL-13 receptors, IL-4Rα, IL-13Rα1 and IL-13Rα2, have been identified in rainbow trout (Oncorhynchus mykiss) and have complex patterns of expression and modulation

    Mammalian interleukin-4 (IL-4) and IL-13 are T helper type 2 (Th2) cytokines with pleiotropic functions in immunity. They signal through receptors containing IL-4Rα and IL-2Rγ or IL-13Rα1. In addition, a decoy...

    Tiehui Wang, Wenshu Huang, Maria M. Costa, Samuel A. M. Martin in Immunogenetics (2011)