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  1. Article

    Open Access

    Embryonic exposure to ethanol increases the susceptibility of larval zebrafish to chemically induced seizures

    Prenatal ethanol exposure is known to cause neurodevelopmental disorders. While high prevalence of epilepsy is observed among the children whose mothers abused alcohol during pregnancy, the results from animal...

    Keling Wang, **aopan Chen, Jie Liu, Li-** Zou, Wenke Feng, Lu Cai in Scientific Reports (2018)

  2. Article

    Open Access

    Activation of autophagy attenuates EtOH-LPS-induced hepatic steatosis and injury through MD2 associated TLR4 signaling

    Autophagy serves as a protective mechanism to degrade damaged organelles and proteins. Acute alcohol exposure is known to activate the hepatic autophagy response, whereas chronic alcohol exposure slows autopha...

    **aoxia Kong, Ying Yang, Li Ren, Tuo Shao, Fengyuan Li, Cuiqing Zhao in Scientific Reports (2017)

  3. Article

    Open Access

    Fibroblast growth factor 21 deficiency exacerbates chronic alcohol-induced hepatic steatosis and injury

    Fibroblast growth factor 21 (FGF21) is a hepatokine that regulates glucose and lipid metabolism in the liver. We sought to determine the role of FGF21 in hepatic steatosis in mice exposed to chronic alcohol tr...

    Yanlong Liu, Cuiqing Zhao, Jian **ao, Liming Liu, Min Zhang in Scientific Reports (2016)