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    Article

    Elevated systemic immune inflammation level increases the risk of total and cause-specific mortality among patients with chronic kidney disease: a large multi-center longitudinal study

    Chronic kidney disease (CKD) is inherently a complex immune-inflammatory condition, and heightened inflammation and immune dysfunction are closely related to an increased risk of death. However, evidence regar...

    Wenguang Lai, Yun **e, **aoli Zhao, **ayan Xu, Sijia Yu, Hongyu Lu in Inflammation Research (2023)

  2. Article

    Open Access

    Association between triglyceride glucose index and worsening heart failure in significant secondary mitral regurgitation following percutaneous coronary intervention

    The triglyceride glucose (TyG) index is an alternative to insulin resistance (IR) as an early indicator of worsening heart failure (HF). Patients with secondary mitral regurgitation (sMR) often experience prog...

    Haozhang Huang, Qiang Li, Jiulin Liu, Linfang Qiao in Cardiovascular Diabetology (2022)

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    Article

    Incidence and mortality of acute kidney disease following coronary angiography: a cohort study of 9223 patients

    Acute kidney disease (AKD) is an important state in the evolving kidney diseases. However, there is limited data on the incidence and prognosis of AKD following coronary angiography (CAG). Therefore, we aim to...

    ** Liu, Qiang Li, Weihua Chen, Haozhang Huang in International Urology and Nephrology (2022)

  4. Article

    Open Access

    A Bioinformatics Investigation into the Pharmacological Mechanisms of Sodium-Glucose Co-transporter 2 Inhibitors in Diabetes Mellitus and Heart Failure Based on Network Pharmacology

    Diabetes mellitus (DM) is a major risk factor for the development of heart failure (HF). Sodium-glucose co-transporter 2 (SGLT2) inhibitors have demonstrated consistent benefits in the reduction of hospitaliza...

    Ziling Mai, Huanqiang Li, Guanzhong Chen, Enzhao Chen in Cardiovascular Drugs and Therapy (2022)

  5. Article

    Open Access

    Independent and joint effects of high-sensitivity c-reactive protein and hypoalbuminemia on long-term all-cause mortality among coronary artery disease: a prospective and multicenter cohort study

    High-sensitivity C-reactive protein (hs-CRP) plays an important role in hypoalbuminemia as a representative of inflammation, which is closely associated with poor prognosis among patients with coronary artery ...

    Haozhang Huang, Yaren Yu, Liling Chen, Shiqun Chen in BMC Cardiovascular Disorders (2021)