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  1. Article

    Open Access

    Exploring the nexus between fatigue, body composition, and muscle strength in hemodialysis patients

    Fatigue is a relatively prevalent condition among hemodialysis patients, resulting in diminished health-related quality of life and decreased survival rates. The purpose of this study was to investigate the re...

    Rui Shi, Jia-xin Zhu, Li Zhu, Wen-man Zhao, Huai Li in European Journal of Medical Research (2024)

  2. Article

    Open Access

    Diosmin ameliorates renal fibrosis through inhibition of inflammation by regulating SIRT3-mediated NF-κB p65 nuclear translocation

    Renal fibrosis is considered an irreversible pathological process and the ultimate common pathway for the development of all types of chronic kidney diseases and renal failure. Diosmin is a natural flavonoid g...

    Wen-Man Zhao, Xun-Liang Li, Yuyu Zhu, Rui Shi in BMC Complementary Medicine and Therapies (2024)

  3. Article

    Open Access

    Analysis of the potential biological mechanisms of diosmin against renal fibrosis based on network pharmacology and molecular docking approach

    Interstitial fibrosis is involved in the progression of various chronic kidney diseases and renal failure. Diosmin is a naturally occurring flavonoid glycoside that has antioxidant, anti-inflammatory, and anti...

    Wen-Man Zhao, Zhi-Juan Wang, Rui Shi, Yuyu Zhu in BMC Complementary Medicine and Therapies (2023)