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Article
A BP Neural Network Based on Improved PSO for Increasing Current Efficiency of Copper Electrowinning
In this paper, to improve the current efficiency in the copper electrowinning process is taken as the research objective. In the traditional production process, sulfate ion concentration, copper ion concentrat...
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Article
Open AccessPredCRP: predicting and analysing the regulatory roles of CRP from its binding sites in Escherichia coli
Cyclic AMP receptor protein (CRP), a global regulator in Escherichia coli, regulates more than 180 genes via two roles: activation and repression. Few methods are available for predicting the regulatory roles fro...
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Article
Open AccessThe loss-of-function mutations and down-regulated expression of ASB3 gene promote the growth and metastasis of colorectal cancer cells
Ankyrin repeat and SOCS box protein 3 (ASB3) is a member of ASB family and contains ankyrin repeat sequence and SOCS box domain. Previous studies indicated that it mediates the ubiquitination and degradation o...
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Article
Open AccessPrediction of linear B-cell epitopes of hepatitis C virus for vaccine development
High genetic heterogeneity in the hepatitis C virus (HCV) is the major challenge of the development of an effective vaccine. Existing studies for develo** HCV vaccines have mainly focused on T-cell immune re...
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Article
Open AccessCharacterizing informative sequence descriptors and predicting binding affinities of heterodimeric protein complexes
Protein-protein interactions (PPIs) are involved in various biological processes, and underlying mechanism of the interactions plays a crucial role in therapeutics and protein engineering. Most machine learnin...
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Article
Open AccessNeuropilin 1 is an entry factor that promotes EBV infection of nasopharyngeal epithelial cells
Epstein–Barr virus (EBV) is implicated as an aetiological factor in B lymphomas and nasopharyngeal carcinoma. The mechanisms of cell-free EBV infection of nasopharyngeal epithelial cells remain elusive. EBV gl...
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Article
Land use change and landslide characteristics analysis for community-based disaster mitigation
On August 8, 2009, Typhoon Morakot brought heavy rain to Taiwan, causing numerous landslides and debris flows in the Taihe village area of Meishan Township, Chiayi County, in south-central Taiwan. In the Taihe...
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Article
Open AccessPrediction and analysis of protein solubility using a novel scoring card method with dipeptide composition
Existing methods for predicting protein solubility on overexpression in Escherichia coli advance performance by using ensemble classifiers such as two-stage support vector machine (SVM) based classifiers and a nu...
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Article
Open AccessPredicting and analyzing DNA-binding domains using a systematic approach to identifying a set of informative physicochemical and biochemical properties
Existing methods of predicting DNA-binding proteins used valuable features of physicochemical properties to design support vector machine (SVM) based classifiers. Generally, selection of physicochemical proper...
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Article
Open AccessProLoc-GO: Utilizing informative Gene Ontology terms for sequence-based prediction of protein subcellular localization
Gene Ontology (GO) annotation, which describes the function of genes and gene products across species, has recently been used to predict protein subcellular and subnuclear localization. Existing GO-based predi...
