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Open AccessGlycoengineering of pertuzumab and its impact on the pharmacokinetic/pharmacodynamic properties
Pertuzumab is an antihuman HER2 antibody developed for HER2 positive breast cancer. Glycosylation profiles are always the important issue for antibody based therapy. Previous findings have suggested the impact...
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Methods to measure and analyze ciliary beat activity: Ca2+ influx-mediated cilia mechanosensitivity
Airway ciliary beat activity (CBA) plays a pivotal role in protecting the body by removing mucus and pathogens from the respiratory tract. Since CBA is complicated and cannot be characterized by merely frequen...
