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  1. No Access

    Article

    4-Phenylbutyric Acid Attenuates Endoplasmic Reticulum Stress-Mediated Intestinal Epithelial Cell Apoptosis in Rats with Severe Acute Pancreatitis

    The present study aimed to determine whether intestinal epithelial cell (IECs) apoptosis could be induced by endoplasmic reticulum stress (ERS) in severe acute pancreatitis (SAP), and the role of chemical chap...

    Yun-dong You, Wen-hong Deng, Wen-yi Guo, Liang Zhao… in Digestive Diseases and Sciences (2019)

  2. No Access

    Article

    12-Month clinical results of drug-coated balloons for de novo coronary lesion in vessels exceeding 3.0 mm

    The purpose of this observational study was to investigate the feasibility, initial safety, and efficacy of the SeQuent® Please DCB (B. Braun Melsungen, Germany) for patients with de novo coronary lesions in v...

    Yi Liu, Yao-Jun Zhang, Long-**ang Deng… in The International Journal of Cardiovascula… (2019)

  3. No Access

    Article

    Insulin inhibits β-adrenergic action in ischemic/reperfused heart: a novel mechanism of insulin in cardioprotection

    Sympathetic overactivity is closely connected with cell injury and contractile dysfunction during myocardial ischemia/reperfusion (MI/R). Insulin exerts protection for the I/R heart and the underlying mechanis...

    Qiu-Jun Yu, Rui Si, Ning Zhou, Hai-Feng Zhang, Wen-Yi Guo, Hai-Chang Wang… in Apoptosis (2008)

  4. No Access

    Article

    Long-term aerobic exercise protects the heart against ischemia/reperfusion injury via PI3 kinase-dependent and Akt-mediated mechanism

    Physical activity has been shown to improve cardiovascular function and to be beneficial to type 2 diabetic patients. However, the effects of aerobic exercise (AE) on myocardial ischemia/reperfusion (MI/R) are...

    Kun-Ru Zhang, Hai-Tao Liu, Hai-Feng Zhang, Quan-Jiang Zhang, Qiu-**a Li… in Apoptosis (2007)

  5. No Access

    Article

    Hypoxic postconditioning enhances the survival and inhibits apoptosis of cardiomyocytes following reoxygenation: role of peroxynitrite formation

    Objectives: Our previous study has shown that slow or “controlled” reperfusion for the ischemic heart reduces cardiomyocyte injury and myocardial infarction, while the mechanisms involved...

    Hai-Chang Wang, Hai-Feng Zhang, Wen-Yi Guo, Hui Su, Kun-Ru Zhang, Qiu-**a Li… in Apoptosis (2006)

  6. Article

    Insulin improves cardiomyocyte contractile function through enhancement of SERCA2a activity in simulated ischemia/reperfusion

    Insulin exerts anti-apoptotic effects in both cardiomyocytes and coronary endothelial cells following ischemia/reperfusion (I/R) via the Akt-endothelial nitric oxide synthase survival signal pathway. This impo...

    Jie Yu, Hai-feng Zhang, Feng Wu, Qiu-xia Li, Heng Ma… in Acta Pharmacologica Sinica (2006)

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  7. No Access

    Article

    Cloning and localization of vip3A gene of Bacillus thuringiensis

    An insecticidal protein gene, vip3A, was cloned from Bacillus thuringiensis strain WB50. The nucleotide sequence of 2,460 bp (GenBank acc. No. AY295778) showed 99% homology with the known vip3A genes. Using speci...

    Zeng Ling Wu, Wen Yi Guo, Jun Zhi Qiu, Tian Pei Huang, Xun Bo Li… in Biotechnology Letters (2004)