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Article
Open AccessNutrient deficiency patterns and all-cause and cardiovascular mortality in older adults with hypertension: a latent class analysis
Previous researches examining the impact of dietary nutrition on mortality risk have mainly focused on individual nutrients, however the interaction of these nutrients has not been considered. The purpose of t...
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Article
Standard Procedure-Guided Flight Trajectory Pattern Mining for Airport Terminal Airspace
Terminal airspace complexity necessitates adherence to standard procedures and instrument flight rules for aircraft arrivals and departures. Standard procedures are responsible for defining the planned traject...
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Article
Rheology and Phase Morphology Properties of Recycled Asphalt Modified with Waste Cooking Oil and Activated Crumb Rubber
To improve the performance of hot mix asphalt (HMA) with recycled asphalt pavement (RAP), it is commonly required to incorporate rejuvenators and modifiers to achieve a superior quality of rejuvenated asphalt....
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Article
Open AccessBiotransformation of zearalenone to non-estrogenic compounds with two novel recombinant lactonases from Gliocladium
The mycotoxin zearalenone (ZEA) produced by toxigenic fungi is widely present in cereals and its downstream products. The danger of ZEA linked to various human health issues has attracted increasing attention....
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Article
Open AccessA landscape of gene expression regulation for synovium in arthritis
The synovium is an important component of any synovial joint and is the major target tissue of inflammatory arthritis. However, the multi-omics landscape of synovium required for functional inference is absent...
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Article
Open AccessGenome-wide association analysis of left ventricular imaging-derived phenotypes identifies 72 risk loci and yields genetic insights into hypertrophic cardiomyopathy
Left ventricular regional wall thickness (LVRWT) is an independent predictor of morbidity and mortality in cardiovascular diseases (CVDs). To identify specific genetic influences on individual LVRWT, we establ...
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Article
Open AccessThe mediating role of psychological capital on the relationship between authentic leadership and nurses’ caring behavior: a cross-sectional study
Caring behavior among nurses would have an impact on patient outcomes. External organizational job resources and personal internal psychological resources are correlated to nurses’ caring behavior. Authentic l...
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Article
Targeting CDH17 with Chimeric Antigen Receptor-Redirected T Cells in Small Cell Lung Cancer
Chimeric antigen receptor T cell (CAR-T) therapy stands as a precise and targeted approach in the treatment of malignancies. In this study, we investigated the feasibility of targeting Cadherin 17 (CDH17) with...
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Article
Open AccessGenome-wide enhancer-gene regulatory maps link causal variants to target genes underlying human cancer risk
Genome-wide association studies have identified numerous variants associated with human complex traits, most of which reside in the non-coding regions, but biological mechanisms remain unclear. However, assign...
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Article
Open AccessPatterns of lymph node metastasis in level IIB and contralateral level VI for papillary thyroid carcinoma with pN1b and safety of low collar extended incision for neck dissection in level II
To explore relevant clinical factors of level IIB and contralateral level VI lymph node metastasis and evaluate the safety of low-collar extended incision (LCEI) for lymph node dissection in level II for papil...
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Article
Open AccessMetagenome sequencing and 103 microbial genomes from ballast water and sediments
The great threat of microbes carried by ballast water calls for figuring out the species composition of the ballast-tank microbial community, where the dark, cold, and anoxic tank environment might select spec...
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Article
Open AccessConstruction of a system for head and neck tumor traceless resection with non-inflatable transaxillary total endoscopic surgery
Radical cure and functional preservation of tumors are the fundamental goals of surgical treatment of head and neck tumors, and the preservation of good aesthetics is a higher pursuit on this basis. Fully hidi...
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Article
HSPA12A was identified as a key driver in colorectal cancer GWAS loci 10q26.12 and modulated by an enhancer–promoter interaction
Although genome-wide association studies (GWASs) have identified over 100 colorectal cancer (CRC) risk loci, an understanding of causal genes or risk variants and their biological functions in these loci remai...
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Article
Open AccessThe relationship between physical exercise and smoking behavior among Chinese residents aged 16 years and older
To explore the relationship between physical exercise and smoking behavior among Chinese residents aged 16 years and older. Analysis based on 29,466 validated cases in the 2018 China Family Panel Studies (CFPS...
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Article
Open AccessL-kynurenine induces NK cell loss in gastric cancer microenvironment via promoting ferroptosis
Natural killer (NK) cells play a major role in body’s fighting against various types of cancers. Their infiltration in the tumor microenvironment (TME) of gastric cancer (GC) are significantly decreased, which...
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Article
Composition and Function of Bacterial Communities of Bryophytes and Their Underlying Sediments in the Dajiuhu Peatland, Central China
Symbiotic microbiomes of Sphagnum have been confirmed to play a fundamental role in carbon and nitrogen cycles, however, little is known about microbiomes associated with other bryophytes in subtropical peatland ...
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Article
Open AccessMolecular Network Analysis Discloses the Limited Contribution to HIV Transmission for Patients with Late HIV Diagnosis in Northeast China
In the “treat all” era, the high rate of late HIV diagnosis (LHD) worldwide remains an impediment to ending the HIV epidemic. In this study, we analyzed LHD in newly diagnosed people living with HIV (PLWH) and...
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Article
Molecular mechanisms of ferroptosis and relevance to inflammation
Inflammation is a defensive response of the organism to irritation which is manifested by redness, swelling, heat, pain and dysfunction. The inflammatory response underlies the role of various diseases. Ferrop...
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Article
Diverse Bathyarchaeotal Lineages Dominate Archaeal Communities in the Acidic Dajiuhu Peatland, Central China
Bathyarchaeota are believed to have roles in the carbon cycle in marine systems. However, the ecological knowledge of Bathyarchaeota is limited in peatland ecosystems. Here, we investigated the vertical distri...
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Chapter and Conference Paper
Formation Patterns of Neogene Reservoir in Chengdao Area
Base on analysis of controlling factors of Neogene reservoir of Chengdao area, The source rock, driving force of migration, transport system, reservoir formed pattern and enrichment law of different block rese...
