8,363 Result(s)
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Article
Open AccessIntegrating lipid metabolite analysis with MRI-based transformer and radiomics for early and late stage prediction of oral squamous cell carcinoma
Oral Squamous Cell Carcinoma (OSCC) presents significant diagnostic challenges in its early and late stages. This study aims to utilize preoperative MRI and biochemical indicators of OSCC patients to predict t...
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On solving a rank regularized minimization problem via equivalent factorized column-sparse regularized models
Rank regularized minimization problem is an ideal model for the low-rank matrix completion/recovery problem. The matrix factorization approach can transform the high-dimensional rank regularized problem to a l...
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Open AccessChoroid plexus volume as a novel candidate neuroimaging marker of the Alzheimer’s continuum
Enlarged choroid plexus (ChP) volume has been reported in patients with Alzheimer’s disease (AD) and inversely correlated with cognitive performance. However, its clinical diagnostic and predictive value, and ...
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Weak Bonded Interface and Shear Block Design for Validating Fracture Caging’s Effect in Induced Seismic Mitigation
Fracture caging is an innovative approach in geothermal energy extraction, utilizing one injection well surrounded by multiple boundary wells for production. This method facilitates high-rate fluid injection a...
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Rapid degradation of thermosetting ester epoxies and monomer recovery methods
The degradation and recycling of waste epoxy resins is an urgent environmental problem, encouraging the use of degradable thermosetting epoxies. In this study, a high-performance thermosetting epoxy resin mate...
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Open AccessCorrection: Low-intensity pulsed ultrasound (LIPUS) enhances the anti-inflammatory effects of bone marrow mesenchymal stem cells (BMSCs)-derived extracellular vesicles
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Open AccessA single-cell chromatin accessibility dataset of human primed and naïve pluripotent stem cell-derived teratoma
Teratoma, due to its remarkable ability to differentiate into multiple cell lineages, is a valuable model for studying human embryonic development. The similarity of the gene expression and chromatin accessibi...
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Open AccessThe value of 68Ga-PSMA PET/CT in the diagnosis of intracapsular prostate cancer with a poor prognosis
To evaluate the diagnostic value of 68Ga-prostate-specific membrane antigen (PSMA) positron emission tomography/computed tomography (PET/CT) for intracapsular prostate cancer with a poor prognosis (PPC) and no ex...
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Effect of Rolling Temperature on the Mechanical Properties and Corrosion Behavior of Mg–Zn–Y–Nd Alloy Thin Sheets
There is a growing demand for degradable membranes with sufficient mechanical properties to guide tissue regeneration in dental surgery. In the present work, a two-stage rolling process in which the first roll...
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Study on the Self-Synchronization and Sommerfeld Effect of Rectangular Thin Plate Vibration System Excited by Double Induction Motors
With the development of vibration equipment towards larger scales and higher frequencies, complex structural vibrations become unavoidable. This paper delves into the Sommerfeld effect and self-synchronization...
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FEZF2 inhibits the growth of triple-negative breast cancer cells through EZH2/PD-L1 and enhances anti-tumor immunity in vivo
Triple-negative breast cancer (TNBC) is characterized by high aggressiveness, heterogeneity, and poor prognosis. Programmed cell death 1 (PD-1)/programmed death-ligand 1 (PD-L1) inhibitors, a crucial type of i...
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Design of a bi-level PSO based modular neural network for multi-step time series prediction
Derived from an effective strategy - direct and multiple-input multiple-output strategy, a modular neural network based on a bi-level particle swarm optimization algorithm (BLPSO-MNN) is proposed in the presen...
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Open AccessA Post-Marketing Surveillance Study of Nusinersen for Spinal Muscular Atrophy in Routine Medical Practice in China: Interim Results
Spinal muscular atrophy (SMA) is a rare, autosomal recessive, neuromuscular disease that leads to progressive muscular weakness and atrophy. Nusinersen, an antisense oligonucleotide, was approved for SMA in Ch...
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Unraveling the influencing mechanism of water ingress on the adhesion behavior of poly(dimethylsiloxane)-silica interface: a molecular dynamic study
Water ingress in nanofiller reinforced polymer nanocomposite is usually considered as one of the causes for the interfacial failure between nanofiller and nanocomposite. However, the molecular mechanism for th...
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Open AccessYAP1 inhibits the senescence of alveolar epithelial cells by targeting Prdx3 to alleviate pulmonary fibrosis
The senescence of alveolar type II (AT2) cells impedes self-repair of the lung epithelium and contributes to lung injury in the setting of idiopathic pulmonary fibrosis (IPF). Yes-associated protein 1 (YAP1) i...
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Identification of autism spectrum disorder using multiple functional connectivity-based graph convolutional network
Presently, the combination of graph convolutional networks (GCN) with resting-state functional magnetic resonance imaging (rs-fMRI) data is a promising approach for early diagnosis of autism spectrum disorder ...
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Single-cell sequencing advances in research on mesenchymal stem/stromal cells
Mesenchymal stem/stromal cells (MSCs), originating from the mesoderm, represent a multifunctional stem cell population capable of differentiating into diverse cell types and exhibiting a wide range of biologic...
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The selection of animal models influences the assessment of anti-tumor efficacy: promising sialic acid-conjugate modified liposomes demonstrate remarkable therapeutic effects in diverse mouse strains
Mice as a crucial tool for preclinical assessment of antineoplastic agents. The impact of physiological differences among mouse strains on the in vivo efficacy of antitumor drugs, however, has been significant...
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Theory, technology and application of grouted bolting in soft rock roadways of deep coal mines
The grouted bolt, combining rock bolting with grouting techniques, provides an effective solution for controlling the surrounding rock in deep soft rock and fractured roadways. It has been extensively applied ...
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Fire danger forecasting using machine learning-based models and meteorological observation: a case study in Northeastern China
Wildfire is one of the primary natural disturbance agents in the forests of China. The forecast of fire danger is critically important to assist stakeholders to avoid and mitigate wildfire-induced hazards and ...