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  1. No Access

    Article

    Bitter taste TAS2R14 activation by intracellular tastants and cholesterol

    Bitter taste receptors, particularly TAS2R14, play central roles in discerning a wide array of bitter substances, ranging from dietary components to pharmaceutical agents1,2. TAS2R14 is also widely expressed in e...

    **aolong Hu, Weizhen Ao, Mingxin Gao, Lijie Wu, Yuan Pei, Shenhui Liu, Yiran Wu… in Nature (2024)

  2. No Access

    Article

    Atypical antipsychotics antagonize GABAA receptors in the ventral tegmental area GABA neurons to relieve psychotic behaviors

    Psychosis is an abnormal mental condition that can cause patients to lose contact with reality. It is a common symptom of schizophrenia, bipolar disorder, sleep deprivation, and other mental disorders. Clinica...

    Chen Lu, **aona Zhu, Yifan Feng, Weizhen Ao, Jie Li, Zilong Gao… in Molecular Psychiatry (2023)