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Article
Open AccessBone marrow mesenchymal stem cell-derived exosomal microRNA-381-3p alleviates vascular calcification in chronic kidney disease by targeting NFAT5
Vascular calcification (VC) is a significant complication of chronic kidney disease (CKD) and cellular apoptosis is one of the intricate mechanisms of VC. Bone marrow mesenchymal stem cell-derived exosome (BMS...
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Article
Metal organic framework derived Zn/N co-doped hydrophilic porous carbon for efficient solid phase microextraction of polar phenols
MOF-derived zink and nitrogen co-doped porous carbon (ZNPC) was synthesized through the pyrolysis of MOF-5-NH2 and used as a solid-phase microextraction (SPME) coating material. Coupled with gas chromatography-ma...
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Article
Acetylation-stabilized chloride intracellular channel 1 exerts a tumor-promoting effect on cervical cancer cells by activating NF-κB
Cervical cancer remains a major cause of cancer-related death in women, especially in develo** countries. Previously, we found that the acetylation levels of chloride intracellular channel 1 (CLIC1) at lysin...
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Article
Open AccessIdentification of lysine acetylome in cervical cancer by label-free quantitative proteomics
Lysine acetylation is a post-translational modification that regulates a diversity of biological processes, including cancer development.
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Article
Open AccessEffect of hyperoside on cervical cancer cells and transcriptome analysis of differentially expressed genes
Hyperoside (Hy) is a plant-derived quercetin 3-d-galactoside that exhibits inhibitory activities on various tumor types. The objective of the current study was to explore Hy effects on cervical cancer cell prolif...
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Article
Bone marrow mesenchymal stem cell–derived exosomes alleviate high phosphorus-induced vascular smooth muscle cells calcification by modifying microRNA profiles
Vascular calcification is a common complication in patients with chronic kidney disease (CKD). It is an important predictor of cardiovascular disease and all-cause mortality. Previous studies have confirmed th...
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Article
Open AccessThe anticancer effects of ferulic acid is associated with induction of cell cycle arrest and autophagy in cervical cancer cells
Ferulic acid (4-hydroxy-3-methoxycinnamic acid, FA) is a hydroxycinnamic acid derived from a rich polyphenolic compound. This study aimed to investigate the effect of ferulic acid (4-hydroxy-3-methoxycinnamic ...
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Article
Therapeutic Effects of NK-HDAC-1, a Novel Histone Deacetylase Inhibitor, on Collagen-Induced Arthritis Through the Induction of Apoptosis of Fibroblast-Like Synoviocytes
The purpose of this study is to investigate the therapeutic effects of a novel histone deacetylase inhibitor (HDACi), NK-HDAC-1, on collagen-induced arthritis (CIA) and pathogenic fibroblast-like synoviocytes ...