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    Article

    Sp1 Regulates Human Huntingtin Gene Expression

    Huntington’s disease (HD) is a hereditary neurodegenerative disorder resulting from the expansion of a polyglutamine tract in the huntingtin protein. The expansion of cytosine–adenine–guanine repeats results i...

    Ruitao Wang, Yawen Luo, Philip T. T. Ly, Fang Cai… in Journal of Molecular Neuroscience (2012)

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    Article

    BACE1 Gene Promoter Single-Nucleotide Polymorphisms in Alzheimer’s Disease

    Alzheimer’s disease (AD) is the most neurodegenerative disorder leading to dementia. Neuritic plaque formation in brains is a hallmark of AD pathogenesis. Amyloid β protein (Aβ) is the central component of neu...

    Weihui Zhou, Fang Cai, Yu Li, George S. Yang… in Journal of Molecular Neuroscience (2010)