5 Result(s)
within
Weihui Zhou
Biomedicine
Cell Biology
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Article
Traumatic Brain Injury Alters the Metabolism and Facilitates Alzheimer’s Disease in a Murine Model
A majority of Alzheimer’s disease (AD) cases are sporadic without known cause. People who suffered from traumatic brain injury (TBI) are more likely to develop neurodegeneration and cognitive impairments. Howe...
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Article
Ethanol Alters APP Processing and Aggravates Alzheimer-Associated Phenotypes
The majority of Alzheimer’s disease (AD) cases are sporadic with unknown causes. Many dietary factors including excessive alcohol intake have been reported to increase the risk to develop AD. The effect of alc...
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Article
Regulation of SET Gene Expression by NFkB
SET is elevated and mislocalized in the neuronal cytoplasm in brains of Alzheimer’s disease (AD) and Down syndrome (DS) patients. Cytoplasm SET leads to inhibition of protein phosphatase 2A and is involved in ...
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Article
Sp1 Regulates Human Huntingtin Gene Expression
Huntington’s disease (HD) is a hereditary neurodegenerative disorder resulting from the expansion of a polyglutamine tract in the huntingtin protein. The expansion of cytosine–adenine–guanine repeats results i...
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Article
BACE1 Gene Promoter Single-Nucleotide Polymorphisms in Alzheimer’s Disease
Alzheimer’s disease (AD) is the most neurodegenerative disorder leading to dementia. Neuritic plaque formation in brains is a hallmark of AD pathogenesis. Amyloid β protein (Aβ) is the central component of neu...
