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Quetiapine ameliorates collagen-induced arthritis in mice via the suppression of the AKT and ERK signaling pathways
To investigate the amelioration effects of quetiapine on rheumatoid arthritis with RAW 264.7 macrophage and collagen-induced arthritis (CIA) DBA/1J mouse model.
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Open AccessActivation-Induced Conformational Changes of Dopamine D3 Receptor Promote the Formation of the Internal Water Channel
The atomic-level dopamine activation mechanism for transmitting extracellular ligand binding events through transmembrane helices to the cytoplasmic G protein remains unclear. In the present study, the complet...
