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Protocol
An Additive-Free Model for Tau Self-Assembly
Tau is a natively unfolded protein that contributes to the stability of microtubules. Under pathological conditions such as Alzheimer’s disease (AD), tau protein misfolds and self-assembles to form paired heli...
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Article
Open AccessQuantification of amyloid fibril polymorphism by nano-morphometry reveals the individuality of filament assembly
Amyloid fibrils are highly polymorphic structures formed by many different proteins. They provide biological function but also abnormally accumulate in numerous human diseases. The physicochemical principles o...
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Engineered synthetic scaffolds for organizing proteins within the bacterial cytoplasm
Two complementary coiled-coil peptides and a bacterial microcompartment shell protein are combined to construct cytoscaffolds within Escherichia coli cells. Targeting enzymes to the cytoplasmic scaffold results i...
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Open AccessThe involvement of dityrosine crosslinking in α-synuclein assembly and deposition in Lewy Bodies in Parkinson’s disease
Parkinson’s disease (PD) is characterized by intracellular, insoluble Lewy bodies composed of highly stable α-synuclein (α-syn) amyloid fibrils. α-synuclein is an intrinsically disordered protein that has the ...
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Open AccessEffect of bio-engineering on size, shape, composition and rigidity of bacterial microcompartments
Bacterial microcompartments (BMCs) are proteinaceous organelles that are found in a broad range of bacteria and are composed of an outer shell that encases an enzyme cargo representing a specific metabolic pro...
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The Estimation of Standard Molar Enthalpies of Solution for VOSO4⋅nH2O(s) in Water and in Aqueous H2SO4
The molar enthalpies of solution of VOSO4⋅3.52H2O(s) at various molalities in water and in aqueous sulfuric acid (0.1 mol⋅kg−1), Δsol H m, were measured by a soluti...
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The Enthalpy of Solution of the Alanine-Based Ionic Liquid [C4mim][Ala]
The molar enthalpies of solution of an alanine-based ionic liquid (IL) [C4mim][Ala], 1-butyl-3-methylimidazolium alanine, containing various amount of water and various molalities Δsol H ...
