6,535 Result(s)
-
Article
MoS2 as a cocatalyst applied in advanced oxidation processes for enhancing degradation of organic pollutants: a review
Fenton technology, as a typical advanced oxidation processes (AOPs), can generate reactive oxygen species (ROS) of strong oxidation capacity to degrade organic pollutants, which has attracted wide attention. H...
-
Article
Open AccessAuthor Correction: ALKBH5-mediated m6A modification of IL-11 drives macrophage-to-myofibroblast transition and pathological cardiac fibrosis in mice
-
Article
Advance on Chinese Medicine for Hypertensive Renal Damage: Focus on the Complex Molecular Mechanisms
Hypertensive renal damage (HRD) is a major cause of end-stage renal disease. Among the causes of end-stage renal disease, HRD accounts for nearly 34% of the total number of cases. Antihypertensive treatment is...
-
Article
Photothermal conversion property studies of polyoxophosphitemolybdate derivatives through microwave-assisted synthesis
Photothermal conversion is one of the key technologies in solar energy collection, seawater desalination, photothermal treatment and other important fields. In order to develop next generation photothermal mat...
-
Article
A new tau dephosphorylation-targeting chimera for the treatment of tauopathies
Abnormal accumulation of hyperphosphorylated tau protein plays a pivotal role in a collection of neurodegenerative diseases named tauopathies, including Alzheimer’s disease (AD). We have recently conceptualize...
-
Article
Open AccessDisturbed intracellular folate homeostasis impairs autophagic flux and increases hepatocytic lipid accumulation
Metabolic associated fatty liver disease (MAFLD), a prevalent liver disorder affecting one-third of the global population, encompasses a spectrum ranging from fatty liver to severe hepatic steatosis. Both gene...
-
Article
Open AccessRegioselective and enantioselective propargylic hydroxylations catalyzed by P450tol monooxygenases
Regioselective and enantioselective hydroxylation of propargylic C-H bonds are useful reactions but often lack appropriate catalysts. Here a green and efficient asymmetric hydroxylation of primary and secondar...
-
Article
Validation of the constitution in Chinese medicine questionnaires with the newly developed blood-vacuity category: a rare Taiwanese case study
The concept of body constitution (BC) is a core notion in traditional Chinese medicine, used in diagnosis, treatment, and prevention; however, there is little standardization in terms of definitions and measur...
-
Article
Dynamic change of metabolic dysfunction-associated steatotic liver disease in patients with hepatitis C virus infection after achieving sustained virologic response with direct-acting antivirals
Information on the dynamics of metabolic dysfunction-associated steatotic liver disease (MASLD) among hepatitis C virus patients achieving sustained virologic response (SVR12) with direct-acting antivirals (DAAs)...
-
Article
Conditional Survival of Patients with Limited-Stage Small Cell Lung Cancer After Surgery: A National Real-World Cohort Study
The prognosis of limited-stage small cell lung cancer (LS-SCLC) after surgery usually is estimated at diagnosis, but how the prognosis actually evolves over time for patients who survived for a predefined time...
-
Article
Characterization of a pangolin SARS-CoV-2-related virus isolate that uses the human ACE2 receptor
Various SARS-CoV-2-related coronaviruses have been increasingly identified in pangolins, showing a potential threat to humans. Here we report the infectivity and pathogenicity of the SARS-CoV-2-related virus, ...
-
Article
Open AccessArtificial Intelligence Application in Skull Bone Fracture with Segmentation Approach
This study aims to evaluate an AI model designed to automatically classify skull fractures and visualize segmentation on emergent CT scans. The model’s goal is to boost diagnostic accuracy, alleviate radiologi...
-
Article
Parkin deficiency promotes liver cancer metastasis by TMEFF1 transcription activation via TGF-β/Smad2/3 pathway
Parkin (PARK2) deficiency is frequently observed in various cancers and potentially promotes tumor progression. Here, we showed that Parkin expression is downregulated in liver cancer tissues, which correlates wi...
-
Article
Open AccessNotoginsenoside R1 promotes Lgr5+ stem cell and epithelium renovation in colitis mice via activating Wnt/β-Catenin signaling
Inflammatory bowel disease (IBD) is characterized by persistent damage to the intestinal barrier and excessive inflammation, leading to increased intestinal permeability. Current treatments of IBD primarily ad...
-
Article
Long-term follow-up of symptom and quality of life changes in patients with narcolepsy during and after the COVID-19 pandemic
The COVID-19 pandemic may have a significant impact on patients with narcolepsy, yet a long-term follow-up study is currently lacking. This study aims to investigate changes in symptom severity and the quality...
-
Article
Design and fabrication of lightweight AlCrFeNiTix compositionally complex alloys with exceptional specific strength
This study focuses on compositionally complex alloys (CCAs), aiming to achieve a balance between high strength and low density for new energy and aerospace applications. The composition of AlCrFeNiTix CCAs is str...
-
Article
Continuous-time quantum walk based on cycle under broken-line decoherent noise
At present, decoherence continuous-time quantum walks are only based on measurement decoherence, but a new broken-line noise model for continuous-time quantum walks on the cycle is proposed. In this scheme, we...
-
Article
Open AccessDevelo** an entrustable professional activity for providing health education and consultation in occupational therapy and examining its validity
Entrustable Professional Activities (EPA)-based assessment is easily and intuitively used in evaluating the learning outcomes of competency-based medical education (CBME). This study aimed to develop an EPA fo...
-
Article
Open AccessTranscriptome profiling of fast/glycolytic and slow/oxidative muscle fibers in aging and obesity
Aging and obesity pose significant threats to public health and are major contributors to muscle atrophy. The trends in muscle fiber types under these conditions and the transcriptional differences between dif...
-
Article
Oncoprotein LAMTOR5-mediated CHOP silence via DNA hypermethylation and miR-182/miR-769 in promotion of liver cancer growth
C/EBP homologous protein (CHOP) triggers the death of multiple cancers via endoplasmic reticulum (ER) stress. However, the function and regulatory mechanism of CHOP in liver cancer remain elusive. We have reporte...