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Open AccessEvaluation of vaccine candidates against Rhodococcus equi in BALB/c mice infection model: cellular and humoral immune responses
Rhodococcus equi (R. equi) is a zoonotic opportunistic pathogen that mainly causes fatal lung and extrapulmonary abscesses in foals and immunocompromised individuals. To date, no commercial vaccine against R. equ...
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Open AccessPublisher Correction: Amplified positive effects on air quality, health, and renewable energy under China’s carbon neutral target
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UAV deployment with grid modeling and adaptive multiple pruning search in complex forest scenarios
Nowadays, unmanned aerial vehicles (UAVs) have achieved rapid development due to their flexible flight modes and broad application prospects, which have played an important role in scenarios such as aerial pho...
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Article
The clinical significance and prognostic value of serum beta-2 microglobulin in adult lymphoma-associated hemophagocytic lymphohistiocytosis: a multicenter analysis of 326 patients
To investigate the prognostic impact of serum beta-2 microglobulin (B2M) in adult lymphoma-associated hemophagocytic lymphohistiocytosis (HLH). The clinical and laboratory characteristics of 326 adult patients...
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Article
Non-singular terminal sliding mode control algorithm design based on extended state observer
This research takes the optical mirror polishing robot as the research object. The optical mirror polishing robot receives complex forces during the grinding process. Operational accuracy can be affected by gr...
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Climate adaptation through crop migration requires a nexus perspective for environmental sustainability in the North China Plain
Crop migration can moderate the impacts of global warming on crop production, but its feedback on the climate and environment remains unknown. Here we develop an integrated framework to capture the climate imp...
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Machine learning for the identification of neoantigen-reactive CD8 + T cells in gastrointestinal cancer using single-cell sequencing
It appears that tumour-infiltrating neoantigen-reactive CD8 + T (Neo T) cells are the primary driver of immune responses to gastrointestinal cancer in patients. However, the conventional method is very time-co...
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Correction: O-GlcNAcylation of melanophilin enhances radiation resistance in glioblastoma via suppressing TRIM21 mediated ubiquitination
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Open AccessProteomic Biomarkers of Intrahepatic Cholestasis of Pregnancy
Intrahepatic cholestasis of pregnancy (ICP) is a pregnancy-specific liver disease, which can lead to adverse fetal outcomes, including preterm labor and intrauterine death. The pathogenesis of ICP is still unc...
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Open AccessAssociation between dietary behavior and puberty in girls
Over the decades the trends of early onset of puberty have been observed in children, particularly in girls. Research evidence has reported diet to be among the most important risk factors for puberty onset. T...
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Open AccessLaCl3-based sodium halide solid electrolytes with high ionic conductivity for all-solid-state batteries
To enable high performance of all solid-state batteries, a catholyte should demonstrate high ionic conductivity, good compressibility and oxidative stability. Here, a LaCl3-based Na+ superionic conductor (Na1−xZr
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Open AccessDS-PACK: Tool assembly for the end-to-end support of controlled access human data sharing
The EU General Data Protection Regulation (GDPR) requirements have prompted a shift from centralised controlled access genome-phenome archives to federated models for sharing sensitive human data. In a data-sh...
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A rim-hook rule for quiver flag varieties
The Abelian/non-Abelian correspondence for cohomology (Martin in Symplectic quotients by a nonabelian group and by its maximal torus. ar**v:math/0001002 [math.SG],...
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Chemical Constituents from the Roots of Cynanchum atratum
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Open AccessFGD1-related Aarskog–Scott syndrome: Identification of four novel variations and a literature review of clinical and molecular aspects
Patients with Aarskog–Scott syndrome (AAS) have short stature, facial anomalies, skeletal deformities, and genitourinary malformations. FYVE, RhoGEF, and PH domain-containing 1 (FGD1) is the only known causative ...
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Open AccessAmplified positive effects on air quality, health, and renewable energy under China’s carbon neutral target
China pledged to achieve carbon neutrality by 2060 to combat global climate change, yet the resulting multi-aspect domestic impacts are not fully analysed due to an incomplete understanding of the underlying a...
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Article
Patterns and controlling factors of decomposition in distal shoot systems by branch order across 10 temperate tree species
Plant litter decomposition is a crucial pathway of the global carbon (C) cycle, and controls the net primary productivity in terrestrial ecosystems. Our understanding of litter decomposition is primarily based...
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Open AccessA MTA2-SATB2 chromatin complex restrains colonic plasticity toward small intestine by retaining HNF4A at colonic chromatin
Plasticity among cell lineages is a fundamental, but poorly understood, property of regenerative tissues. In the gut tube, the small intestine absorbs nutrients, whereas the colon absorbs electrolytes. In a st...
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Multi-center study of COVID-19 infection in elderly patients with lymphoma: on behalf of Jiangsu Cooperative Lymphoma Group (JCLG)
Elderly patients with lymphoproliferative diseases (LPD) are vulnerable to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Here, we retrospectively described the clinical features and o...
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A novel SOX10 mutation causing Waardenburg syndrome type 2 by expressing a truncated and dysfunctional protein in a Chinese child
This study aimed to identify the causative variants in a patient with Waardenburg syndrome (WS) type 2 using whole exome sequencing (WES).
