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1,002 Result(s)
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Open AccessDevelopment and validation of a predictive model for double-J stent encrustation after upper urinary tract calculi surgery
The study is aimed to establish a predictive model of double-J stent encrustation after upper urinary tract calculi surgery. We collected the clinical data of 561 patients with indwelling double-J tubes admitt...
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Retraction Note: Fast and robust absolute camera pose estimation with known focal length
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Module partition for complex products based on stable overlap** community detection and overlap** component allocation
The rationality of product module partition is crucial to the success of modular design. The correlations between components of complex products are complex, increasing the difficulty of module partition. Thus...
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Open AccessDietary ellagic acid therapy for CNS autoimmunity: Targeting on Alloprevotella rava and propionate metabolism
Mediterranean diet rich in polyphenolic compounds holds great promise to prevent and alleviate multiple sclerosis (MS), a central nervous system autoimmune disease associated with gut microbiome dysbiosis. Hea...
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Open AccessEngineered extracellular vesicles for targeted reprogramming of cancer-associated fibroblasts to potentiate therapy of pancreatic cancer
Pancreatic cancer is one of the deadly malignancies with a significant mortality rate and there are currently few therapeutic options for it. The tumor microenvironment (TME) in pancreatic cancer, distinguishe...
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Retrospective study of 189 cases of acute perforated peptic ulcer: safety and efficacy of over-the-scope-clip based endoscopic closure
To compare the clinical outcomes in patients with acute perforated peptic ulcer (PPU) treated with over-the-scope clip (OTSC), non-surgical, and surgical interventions, and to explore the effectiveness and saf...
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Open AccessCheek alveolar soft part sarcoma recurrence at the primary site during follow-up: a case report and review of the literature
Alveolar soft part sarcoma (ASPS) occurs most often in the deep muscles or fascia of the extremities in adults, with only 3.4% of these tumours originating from the head, face and neck. To date, only 17 cases ...
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Open AccessDAB2IP inhibits glucose uptake by modulating HIF-1α ubiquitination under hypoxia in breast cancer
Metabolic reprogramming has become increasingly important in tumor biology research. The glucose metabolic pathway is a major energy source and is often dysregulated in breast cancer. DAB2IP is widely reported...
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HRDC challenge: a public benchmark for hypertension and hypertensive retinopathy classification from fundus images
Hypertensive retinopathy (HR) can potentially lead to vision loss if left untreated. Early screening and treatment are critical in reducing the risk of vision loss. The computer-aided diagnostic system present...
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Open AccessMechanism and bioinformatics analysis of the effect of berberine-enhanced fluconazole against drug-resistant Candida albicans
Biofilms produced by Candida albicans present a challenge in treatment with antifungal drug. Enhancing the sensitivity to fluconazole (FLC) is a reasonable method for treating FLC-resistant species. Moreover, sev...
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Ceramic-based meta-material absorber with high-temperature stability
With the continuous exploration of uncharted and extreme environments, enhanced temperature robustness of passive devices has become particularly important. In this study, a ceramic-based meta-material absorbe...
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Enhance the Performance of Directional Feature-based Palmprint Recognition by Directional Response Stability Measurement
Palmprint recognition is an emerging biometrics technology that has attracted increasing attention in recent years. Many palmprint recognition methods have been proposed, including traditional methods and deep...
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The Crystallization Behavior of L-Poly(lactic acid)/Polypropylene Blends: The Acceleration for Both L-Poly(lactic acid) and Polypropylene
For a polymer/polymer dismissible blend with two crystallizable components, the crystallization behavior of different components and the reciprocal influences between different crystals are interesting and imp...
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Open AccessAc2-26 reduced the liver injury after cardiopulmonary bypass in rats via AKT1/GSK3β/eNOS pathway
About 10% of patients after cardiopulmonary bypass (CPB) would undergo acute liver injury, which aggravated the mortality of patients. Ac2-26 has been demonstrated to ameliorate organic injury by inhibiting in...
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Open AccessEconomic Evaluation of Nirmatrelvir/Ritonavir Among Adults Against Hospitalization During the Omicron Dominated Period in Malaysia: A Real-World Evidence Perspective
Nirmatrelvir/ritonavir was administered orally to manage mild to moderate symptoms of COVID-19 in adult patients. The objectives of this study were to (i) evaluate the cost-effectiveness of prescribing nirmatr...
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An integrated investigation of sulfotransferases (SULTs) in hepatocellular carcinoma and identification of the role of SULT2A1 on stemness
The cytosolic sulfotransferases (SULTs) are phase II conjugating enzymes, which are widely expressed in the liver and mainly mediate the sulfation of numerous xenobiotics and endogenous compounds. However, the...
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Open AccessComparative profiling of serum, urine, and feces bile acids in humans, rats, and mice
Bile acids (BAs) play important pathophysiological roles in both humans and mammalian animals. Laboratory rats and mice are widely used animal models for assessing pharmacological effects and their underlying ...
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A new gold(I) phosphine complex induces apoptosis in prostate cancer cells by increasing reactive oxygen species
Thioredoxin reductase (TrxR) is a pivotal regulator of redox homeostasis. It is frequently overexpressed in various cancer cells, including prostate cancer, making it a promising target for the development of ...
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Open AccessCalibration of satellite typhoon data based on attitude modified buoy
To address the issue of poor accuracy in typhoon wind data, this paper presents a methodology for the calibration of typhoon wind data while conducting an analysis and evaluation of the associated uncertaintie...
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Open AccessAc2-26 activated the AKT1/GSK3β pathway to reduce cerebral neurons pyroptosis and improve cerebral function in rats after cardiopulmonary bypass
Cardiopulmonary bypass (CPB) results in brain injury, which is primarily caused by inflammation. Ac2-26 protects against ischemic or hemorrhage brain injury. The present study was to explore the effect and mec...