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Open AccessBioorthogonal Engineered Virus-Like Nanoparticles for Efficient Gene Therapy
A virus-like nanoparticle (reBiosome) was developed via site-specific codon mutation for displaying unnatural amino acid (Azi) on virus envelope protein at a rational site,...
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Reference Work Entry At a glance
Correction to: Liposome-Based Drug Delivery Systems
The copyright holder of this book has been updated to Springer Nature Singapore 2022
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Reference Work Entry In depth
Liposomes in Drug Delivery: Status and Advances
Liposomal drug delivery system has made evident breakthrough and innovation in the fields of drug treatment. The objectives of this chapter are to briefly review the features, classification, major preparation...
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Reference Work Entry In depth
Preparation and Characterization of DNA Liposomes Vaccine
Genetic immunization is a process that uses plasmid DNA encoding antigens from bacteria, viruses, protozoa, and cancers to establish protective humoral and cell-mediated immunity system. The introducing antige...
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Reference Work Entry In depth
Coupling Methods of Antibodies and Ligands for Liposomes
This chapter describes the preparations of coupling methods of antibodies and ligands for targeted drug conjugates and for targeted drug liposomes. To prepare antibody-mediated targeting drug (referring to as ...
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Book and Reference Work
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Article
Open AccessGene regulations and delivery vectors for treatment of cancer
Resistant residual cancer and cancer stem cells after comprehensive treatment often result in the recurrence of cancer. The refractory nature of cancer is an important scientific problem to be solved.
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Book and Living Reference Work (Continuously updated edition)
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Article
Open AccessDevelopment of functional dendrisomes based on a single molecule of polyesterbenzylether dendrimer and their application in cancer stem cell therapy
The differentiation therapy of breast cancer stem cells (CSCs) represents a significant strategy to treat cancer, but inefficient delivery to CSCs hinders the efficacy of differentiation agents. In this work, ...
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Living Reference Work Entry In depth
Coupling Methods of Antibodies and Ligands for Liposomes
This chapter describes the preparations of coupling methods of antibodies and ligands for targeted drug conjugates and for targeted drug liposomes. To prepare antibody-mediated targeting drug (referring to as ...
-
Living Reference Work Entry In depth
Preparation and Characterization of DNA Liposomes Vaccine
Genetic immunization is a process that uses plasmid DNA encoding antigens from bacteria, viruses, protozoa, and cancers to establish protective humoral and cell-mediated immunity system. The introducing antige...
-
Living Reference Work Entry In depth
Liposomes in Drug Delivery: Status and Advances
Liposomal drug delivery system has made evident breakthrough and innovation in the fields of drug treatment. The objectives of this chapter are to briefly review the features, classification, major preparation...
-
Article
Open AccessLipid vesicles containing transferrin receptor binding peptide TfR-T12 and octa-arginine conjugate stearyl-R8 efficiently treat brain glioma along with glioma stem cells
Surgery and radiotherapy cannot fully remove brain glioma; thus, chemotherapy continues to play an important role in treatment of this illness. However, because of the restriction of the blood-brain barrier (B...
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Article
Advances in investigations on the mechanism of cancer multidrug resistance and the liposomes-based treatment strategy
Multidrug resistance is a major cause that leads to the refractory of cancers after a combination strategy by chemotherapy, radiation and surgical treatment. Among the comprehensive treatment, chemotherapy sti...
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Article
Naringenin Enhances the Anti-Tumor Effect of Doxorubicin Through Selectively Inhibiting the Activity of Multidrug Resistance-Associated Proteins but not P-glycoprotein
Naringenin has shown paradoxical results to modulate the function of multidrug resistance-associated proteins (MRPs). The aim of this study is to interpret whether naringenin can reverse intrinsic and/or acqui...
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Article
Effects on the bones of vanadyl acetylacetonate by oral administration: a comparison study in diabetic rats
Oral delivery, rather than parenteral administration, would be beneficial for treating diabetic mellitus owing to the need for a long-term regimen. The objectives of this study were to evaluate oral delivery t...
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Article
Permeation-enhancing effects of chitosan formulations on recombinant hirudin-2 by nasal delivery in vitro and in vivo
To investigate the enhancing effects of chitosan with or without enhancers on nasal recombinant hirudin-2 (rHV2) delivery in vitro and in vivo, and to evaluate the ciliotoxicity of these formulations.
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Article
Enhanced Intracellular Uptake of Sterically Stabilized Liposomal Doxorubicin in Vitro Resulting in Improved Antitumor Activity in Vivo
To investigate the correlation between the in vitro intracellular uptake and the in vivo antitumor activity of anticancer drugs delivered by sterically stabilized liposomes (SSL).
