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  1. No Access

    Article

    Feasibility, endocrine and anti-tumour effects of a triple endocrine therapy with tamoxifen, a somatostatin analogue and an antiprolactin in post-menopausal metastatic breast cancer: a randomized study with long-term follow-up

    Suppression of the secretion of prolactin, growth hormone and insulin-like growth factor 1 (IGF-1) might be important in the growth regulation and treatment of breast cancer. Because oestrogens may counteract ...

    M Bontenbal, JA Foekens, SWJ Lamberts, FH de Jong… in British Journal of Cancer (1998)

  2. No Access

    Article

    Peripheral neuropathy induced by combination chemotherapy of docetaxel and cisplatin

    Docetaxel, a new semisynthetic taxoid that has demonstrated promising activity as an antineoplastic agent, was administered in combination with cisplatin to 63 patients in a dose-escalating study. As both drug...

    PHE Hilkens, LC Pronk, J Verweij, CJ Vecht, WLJ van Putten… in British Journal of Cancer (1997)

  3. No Access

    Article

    Relationship of PS2 with response to tamoxifen therapy in patients with recurrent breast cancer

    PS2, an oestrogen-inducible protein, was measured in the cytosol of 230 primary tumours from patients who were subjected to first-line tamoxifen therapy for advanced disease without prior adjuvant therapy with...

    JA Foekens, H Portengen, MP Look, WLJ van Putten, B Thirion… in British Journal of Cancer (1994)

  4. No Access

    Article

    Prognostic value of cytosolic tyrosine kinase activity in 249 node-positive breast cancer patients

    Tyrosine-specific protein kinase (TPK) has been associated with the cytoplasmic domain of growth factor receptors as well as oncoproteins. Enzymatic activation appears to be a major initial event in these sign...

    S Romain, O Chinot, JGM Klijn, WLJ van Putten, O Guirou… in British Journal of Cancer (1994)

  5. No Access

    Article

    Response to adjuvant chemotherapy in primary breast cancer: no correlation with expression of glutathione S-transferases

    Of 139 node-positive breast cancer patients treated with adjuvant chemotherapy, the pre-treatment levels of glutathione S-transferase (GST) classes alpha, mu and pi, were determined by immuno-quantification on...

    WHM Peters, HMJ Roelofs, WLJ van Putten, JBMJ Jansen… in British Journal of Cancer (1993)

  6. No Access

    Article

    Prognostic value of serum thymidine kinase, tissue polypeptide antigen and neuron specific enolase in patients with small cell lung cancer

    In a group of seventy patients with small cell lung cancer the prognostic value of serum tumour markers was determined. Thymidine kinase (TK), tissue polypeptide antigen (TPA) and lactate dehydrogenase (LDH) b...

    A van der Gaast, WLJ van Putten, R Oosterom, M Cozijnsen… in British Journal of Cancer (1991)