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Article
3D printing redefines microneedle fabrication for transdermal drug delivery
Microneedles (MNs) have emerged as an innovative, virtually painless technique for intradermal drug delivery. However, the complex and costly fabrication process has limited their widespread accessibility, esp...
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Article
Prenatal ultrasonic diagnosis of esophageal atresia and tracheoesophageal fistula combined with interrupted inferior vena cava: a rare case report
This is an extremely rare case of complicated fetal esophageal atresia (EA) with tracheoesophageal fistula (TEF) and interrupted inferior vena cava (IVC) diagnosed by prenatal ultrsonography and successfully t...
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Article
Correction to: P2 purinergic receptors regulate the progression of colorectal cancer
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Article
The functional role of P2 purinergic receptors in the progression of gastric cancer
Studies have confirmed that P2 purinergic receptors (P2X receptors and P2Y receptors) expressed in gastric cancer (GC) cells and GC tissues and correlates with their function. Endogenous nucleotides including ...
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Article
Open AccessProteomic analysis of mitochondria associated membranes in renal ischemic reperfusion injury
The mitochondria and endoplasmic reticulum (ER) communicate via contact sites known as mitochondria associated membranes (MAMs). Many important cellular functions such as bioenergetics, mitophagy, apoptosis, a...
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Article
Selective photosynthesis of imines from biomass-derived aldehydes over Ni/TiO2
Photocatalytic reductive amination of biomass-derived aldehydes is a desirable way to selectively upgrade biomass into value-added nitrogen-containing chemicals under mild conditions. However, it is challengin...
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Article
P2 purinergic receptors regulate the progression of colorectal cancer
More and more studies have revealed that P2 purinergic receptors play a key role in the progression of colorectal cancer (CRC). P2X and P2Y purinergic receptors can be used as promoters and regulators of CRC a...
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Article
Effect of P2X purinergic receptors in tumor progression and as a potential target for anti-tumor therapy
The development of tumors is a complex pathological process involving multiple factors, multiple steps, and multiple genes. Their prevention and treatment have always been a difficult problem at present. A lar...
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Article
Association between the rs3751143 polymorphism of P2RX7 gene and chronic lymphocytic leukemia: A meta-analysis
Meta-analysis was used to determine the association between rs3751143 polymorphism of P2RX7 gene and the risk of chronic lymphocytic leukemia (CLL).
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Article
Open AccessIdentifying risk factors for chronic kidney disease stage 3 in adults with acquired solitary kidney from unilateral nephrectomy: a retrospective cohort study
We aimed to examine the risk factors for chronic kidney disease (CKD) stage 3 among adults with ASK from unilateral nephrectomy.
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Article
Enhancement of the surface free energy of PDMS for reversible and leakage-free bonding of PDMS–PS microfluidic cell-culture systems
Polydimethylsiloxane (PDMS) has become one of the most widely used materials in the fabrication of microfluidic systems bonded onto glass substrates, especially for cell biology applications. However, PDMS is ...
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Article
Open AccessChemotherapy-induced niche perturbs hematopoietic reconstitution in B-cell acute lymphoblastic leukemia
Considerable efforts have been devoted toward the uncovering of the molecular mechanisms underlying the maintenance of hematopoietic stem cells (HSCs) by the normal bone marrow (BM) niche. Previously, we demon...
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Article
Synthesis and Luminescence Properties of Immobilized Europium β-CD Complexes on Silica
Functionalized silica gel organic–inorganic hybrid materials based on covalently grafted lanthanide coordinations onto organosilicone have been the subject of intense study due to their superior physicochemica...
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Article
Multi-Exposure Motion Estimation Based on Deep Convolutional Networks
In motion estimation, illumination change is always a troublesome obstacle, which often causes severely performance reduction of optical flow computation. The essential reason is that most of estimation method...
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Article
Yimu San improves obstetric ability of pregnant mice by increasing serum oxytocin levels and connexin 43 expression in uterine smooth muscle
Prolonged farrowing remains one of the critical challenges in intensive pig farming. This study aims to explore the effects and mechanism of Yimu San (YMS), a Chinese veterinary medicine micro mist, on deliver...
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Article
CT and MRI findings of primitive neuroectodermal tumor in the maxillofacial region
To summarize the computed tomography (CT) and magnetic resonance imaging (MRI) findings of rare primitive neuroectodermal tumors (PNETs) in the maxillofacial region.
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Article
A surface curvature oscillation model for vapour–liquid–solid growth of periodic one-dimensional nanostructures
While the vapour–liquid–solid process has been widely used for growing one-dimensional nanostructures, quantitative understanding of the process is still far from adequate. For example, the origins for the gro...
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Article
Open AccessA group LASSO-based method for robustly inferring gene regulatory networks from multiple time-course datasets
As an abstract map** of the gene regulations in the cell, gene regulatory network is important to both biological research study and practical applications. The reverse engineering of gene regulatory network...
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Article
Influence of annealing temperature on the structural and optical properties of highly-oriented Al and Er co-doped ZnO films
High-quality c-axis oriented 7 mol% Al and 1.5 mol% Er co-doped ZnO films (ZEAO) were prepared on the quartz glass substrates by using sol–gel method. The influence of the annealing temperature on the crystal ori...
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Article
Modeling and In Vitro Experimental Validation for Kinetics of the Colonoscope in Colonoscopy
Colonoscopy is the most sensitive and specific means for detection of colon cancers and polyps. To make colonoscopy more effective several problems must be overcome including: pain associated with the procedur...