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Article
Tryptophan degradation in autoimmune diseases
Recent evidence points to tryptophan (Trp) degradation as a potent immunosuppressive mechanism involved in the maintenance of immunological tolerance. Both Trp depletion and downstream Trp catabolites (TCs) ap...
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Article
BCL-xL: time-dependent dissociation between modulation of apoptosis and invasiveness in human malignant glioma cells
Conditionally BCL-xL-overexpressing LNT-229 Tet-On glioma cell clones were generated to investigate whether the ‘antiapoptosis phenotype’ and the ‘motility phenotype’ mediated by BCL-2 family proteins in glioma c...