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Open AccessDolphin CONTINUE: a multi-center randomized controlled trial to assess the effect of a nutritional intervention on brain development and long-term outcome in infants born before 30 weeks of gestation
Preterm born infants are at risk for brain injury and subsequent developmental delay. Treatment options are limited, but optimizing postnatal nutrition may improve brain- and neurodevelopment in these infants....
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Article
Open AccessFecal amine metabolite analysis before onset of severe necrotizing enterocolitis in preterm infants: a prospective case–control study
Infants develo** necrotizing enterocolitis (NEC) have a different metabolomic profile compared to controls. The potential of specific metabolomics, i.e. amino acids and amino alcohols (AAA), as early diagnos...
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Article
Open AccessCongenital anomalies and genetic disorders in neonates and infants: a single-center observational cohort study
Neonates with genetic disorders or congenital anomalies (CA) contribute considerably to morbidity and mortality in neonatal intensive care units (NICUs). The objective of this study is to study the prevalence ...
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Open AccessSustainable neonatal CLABSI surveillance: consensus towards new criteria in the Netherlands
Central line-associated bloodstream infections (CLABSI) are a main focus of infection prevention and control initiatives in neonatal care. Standardised surveillance of neonatal CLABSI enables intra- and interf...
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Comprehensive state-of-the-art overview of neonatologist performed echocardiography: Steps towards standardization of the use of echocardiography in neonatal intensive care
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Clinician performed ultrasound in fetal growth restriction: fetal, neonatal and pediatric aspects
Fetal growth restriction (FGR) affects 7–10% pregnancies. Conventional and tissue Doppler imaging has noted cardiac compromise during fetal and early neonatal periods in this cohort. In this article, we discus...
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Article
Open AccessEstimation of extravascular lung water using the transpulmonary ultrasound dilution (TPUD) method: a validation study in neonatal lambs
Increased extravascular lung water (EVLW) may contribute to respiratory failure in neonates. Accurate measurement of EVLW in these patients is limited due to the lack of bedside methods. The aim of this pilot ...
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Gold standard must be solid gold
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220 Assessing Cardiac Output and Derived Blood Volumes in a Neonatal Lamb Model with a Left-To-Right Shunt
Aims: To assess cardiac output and derived blood volumes in lambs with a left-to-right shunt using the ultrasound dilution technique (UDCO).
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209 Cardiac Output Measurement in Juvenile Animals with a Surgically Constructed Extra Cardiac Left-To-Right Shunt Using the Transpulmonary Thermodilution Technique
Introduction: Cardiac output measurement using the transpulmonary thermodilution (TPTD) technique is considered the gold standard in pediatric patients in no-shunt circulation. Goal of this study was to valida...
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Article
Myopathology in patients with a Noonan phenotype
Two patients with a Noonan phenotype and progressive hypertrophic obstructive cardiomyopathy are described, in whom abnormal histopathological changes in striated musculature were detected. In both patients a...