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Chemokines, receptors, and their role in cardiovascular pathology
A superfamily of leukocyte chemotactic proteins, known as chemokines, has been identified during the past decade. Chemokines selectively attract and activate different leukocyte subpopulations and are key medi...
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Open AccessThe G-protein-coupled formylpeptide receptor FPR confers a more invasive phenotype on human glioblastoma cells
The G-protein-coupled formylpeptide receptor (FPR) that mediates chemotaxis of phagocytic leucocytes induced by bacterial and host-derived chemotactic peptides is selectively expressed by highly malignant huma...
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Open AccessLong non-coding RNA CCAT1 promotes gallbladder cancer development via negative modulation of miRNA-218-5p
Protein-coding genes account for only ~2% of the human genome, whereas the vast majority of transcripts are non-coding RNAs (ncRNAs) including long ncRNAs (lncRNAs). A growing volume of literature has proposed...
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Open AccessHumanized anti-CD25 monoclonal antibody treatment of steroid-refractory acute graft-versus-host disease: a Chinese single-center experience in a group of 64 patients