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Article
Abstracts Second Congress of the European Society for Clinical Neuropharmacology
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Chapter and Conference Paper
Chronic TVP-1012 (rasagiline) dose — activity response of monoamine oxidases A and B in the brain of the common marmoset
The stereospecific form of the known acetylenic mechanismbased MAO-inhibitor AGN1135 (Rasagiline, TVP-1012) is devoid of sympathomimetic amphetamine-like properties.
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Article
Monoamine oxidase-inhibition and MPTP-induced neurotoxicity in the non-human primate: comparison of rasagiline (TVP 1012) with selegiline
The neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) has been shown to induce parkinsonism in man and non-human primates. Monoamine-oxidase B (MAO-B) has been reported to be implicated in both M...
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Chapter and Conference Paper
Der Nachweis der minimal residualen Tumorerkrankung beim metastasierenden Magenkarzinom in der Nacktmaus eignet sich zur Überprüfung neuer Therapieansätze
Trotz veränderter Therapiekonzepte weisen Karzinome des Magens auch bei vermeintlich kurativer Resektion (RO) eine hohe Rezidivrate und Metastasierungstendenz auf. Als Ursache hierfür kommt die minimal residua...
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Article
Laparoscopic Nissen repair: indications, techniques and long-term benefits
The Nissen fundoplication or total 360° fundoplication is probably the most frequently used anti-reflux procedure throughout the world. With the advent of laparoscopic surgery the popularity among surgeons to ...
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Chapter
Indication for Antireflux Surgery
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Article
NOTES als Zukunftsmodel für die Adipositaschirurgie
Der Trend in der Chirurgie, das Trauma des Zugangsweges zum Zielorgan einer Operation zu minimieren, hält an. Gerade adipöse Patienten profitierten unter der Voraussetzung einer sicheren Durchführung durch ein...
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Article
Bilan diagnostique du RGO: modalités en vue d’optimiser la chirurgie anti-reflux
Dans les pays occidentaux, le recours au traitement anti-reflux par chirurgie mini-invasive, a triplé au cours de ces 15 dernières années. Une telle progression n’a été possible que par une mise au point diagn...
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Article
Endoscopic full-thickness plication for the treatment of gastroesophageal reflux disease using multiple Plicator implants: 12-month multicenter study results
The full-thickness Plicator® (Ethicon Endosurgery, Sommerville, NJ, USA) was developed for endoscopic treatment of gastroesophageal reflux disease (GERD). The goal is to restructure the antireflux barrier by deli...
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Chapter
Antirefluxchirurgie
Die gastroösophageale Refluxkrankheit ist in den westlichen Industrieländern eine sehr häufige Erkrankung und liegt mit der Prävalenz bei 10 % der Bevölkerung, wenn man von der Definition ausgeht, dass mehrmal...
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Article
Benigne Erkrankungen des Ösophagus
Unter den gutartigen Funktionsstörungen der Speiseröhre und des Magens sind die gastroösophageale Refluxkrankheit, die Achalasie und der diffuse Ösophagusspasmus die häufigsten Erkrankungen. Die chirurgische T...
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Article
Euro-NOTES Status Paper: from the concept to clinical practice
The concept of natural orifice transluminal endoscopic surgery (NOTES) consists of the reduction of access trauma by using a natural orifice access to the intra-abdominal cavity. This could possibly lead to le...
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Article
The Potential and Perspective of Peroral Endoscopic Esophageal Myotomy for Achalasia
The therapeutic spectrum of this disorder consists of medical therapy, endoscopic balloon dilatation, endoscopic Botox injection, open or laparoscopic cardia myotomy, and most recently transesophageal endoscop...
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Chapter
NOTES and Hybrid NOTES Procedures in Clinical Practice
Natural orifice transluminal endoscopic surgery (NOTES) has emerged in the early 2000 as a logic development of ideas originating from interventional endoscopists and gastroenterologists as well as surgeons. A...
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Chapter
Surgical Technique and Difficult Situations from Karl-Hermann Fuchs
The terms paraesophageal hernia, large hiatal hernia, upside-down stomach, and mixed hiatal hernia are used sometimes with a remarkable amount of confusion without a clear differentiation. However, these diffe...
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Chapter
Surgical Technique and Difficult Situations from Karl-Hermann Fuchs (Laparoscopic Resection Rectopexy)
A frequent problem in pelvic floor disorders is internal or external rectal prolapse situation. The operative treatment for these functional anatomic changes has been established by laparoscopic resection rect...