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Enzymatic activity and thermoresistance of improved microbial transglutaminase variants
Microbial transglutaminase (MTG, EC 2.3.2.13) of Streptomyces mobaraensis is widely used in industry for its ability to synthesize isopeptide bonds between the proteinogenic side chains of glutamine and lysine. T...
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Chapter
Processing of Diaspore Bauxites
Diaspore bauxites of different origin were processed in tube digestion systems.
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Open AccessThe membrane bound aromatic p-hydroxybenzoic acid oligoprenyltransferase (UbiA) - how iterative improvements lead to a realistic structure that offers new insights into functional aspects of prenyl transferases and terpene synthases
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Open AccessA detailed aanalysis of diphosphate binding sites in proteins
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Open AccessA distance-based method for evaluating protein-structures
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Chapter
The Specificity of DP IV for Natural Substrates is Peptide Structure Determined
Our results indicate that the substrate properties of peptides are encoded by their own structure. That means, that substrate characteristics depend not only on the primary structure around the catalytic site ...
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Article
A very early onset of respiratory failure due to phenytoin-associated hypersensitivity syndrome and concomitant glucocorticoid administration
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Article
The solution conformation of cyclic β-casomorphin-5 analogues
The solution conformation of two cyclicβ-casomorphin-5 analogues H-Tyr-c(-d-Orn-Phe-Pro-Gly-)1 and H-Tyr-c(-Orn-Phe-Pro-Gly-)2 in DMSO-d 6 was studied by NMR spectroscopy and accompanying force field calculations...
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Article
Effects of interleukin-6 (IL-6) and transforming growth factor-β (TGF-β) on neutrophil elastase release
The proinflammatory cytokine interleukin-6 (IL-6) and its potential opponent, transforming growth factor-β (TGF-β 1), have been discussed as being involved in the regulation of inflammatory processes following tr...
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Article
The probable conformation of substrates recognized by dipeptidyl-peptidase IV and some aspects of the catalytic mechanism derived from theoretical investigations
By theoretical conformational investigations of substrates and nonsubstrates of the enzyme dipeptidyl-peptidase IV (DP IV) as well as dipeptide-esters using the ECEPP83 method we determined the structure of pe...
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Varia
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Electric-field-enhanced positronium formation in condensed matter
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Article
The dual action of oxyfedrine on cardiac contractility
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Oxyfedrine, at concentrations of 10−7 to 3×10−6 mol/l, increased the force of contraction of the isolated pap...
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Chapter
Electron Pick Up by Protons Emerging from Solid Surfaces
From experimental evidence it follows that the neutral fraction ϕ0 of protons emerging from a solid surface with energy <1 MeV depends on the proton velocity v1 but hardly on target atomic number Z2.
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Z1 3-Dependent Stop** Power and Range Contributions
The stop** power of a target, composed of atoms with atomic number Z2, for a projectile of charge Z1e and velocity v1, depends in first Born approximation on the projectile charge as (Z1e)2. Recently [1], we ex...
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Article
A postsynaptic effect of tyramine in ventricular muscle
Tachyphylaxis and susceptibility to pretreatment with reserpine demonstrate that tyramine increases contractility of the guinea-pig papillary muscle in concentrations up to 10−4 M by means of an indirect sympatho...
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“Supramaximal” enhancement of the inotropic effect of noradrenaline by tyramine
The positive inotropic effect of noradrenaline on the guinea-pig papillary muscle is potentiated in the presence of 1×10−5 M tyramine, the concentration of noradrenaline that is necessary to produce a half maxima...
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Abstracts
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Säure-Basenstatus und Atemgasdrucke des mütterlichen und fetalen Blutes sowie fetale Herz-frequenz und Wehentätigkeit nach paracervicalem Block mit Bupivacain (Carbostesin): Eine Untersuchung im doppelten Blindversuch
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Chapter
Fluor-Komplexe
Beim Fluor liegen die Verhältnisse insofern anders als beim Sauerstoff, als das F−-Ion bei etwa gleicher Größe eine Ladung weniger trägt als das O2−-Ion. Infolgedessen kann man in Fluorkomplexsalzen bei der Koord...