Critical Issues in Head and Neck Oncology
Key Concepts from the Eighth THNO Meeting
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Open AccessClinical evaluation of a web-based personalized recommendation system with electronic health record interface to optimize healthcare resources during SARS-CoV-2 surges
During the SARS-CoV-2 pandemic, the German healthcare system faced challenges of efficiently allocating testing resources. To address this, we developed an open-source personalized recommendation system (PRS) ...
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Open AccessRobotic stereotactic body radiotherapy for the management of adrenal gland metastases: a bi-institutional analysis
Adrenal gland metastases (AGMs) are a common manifestation of metastatic tumor spread, especially in non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC). In patients with a limited systemic tu...
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Book and Conference Proceedings
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Article
Open AccessPreoperative hypofractionated radiotherapy for soft tissue sarcomas: a systematic review
Soft tissue sarcomas (STS) represent a diverse group of rare malignant tumors. Currently, five to six weeks of preoperative radiotherapy (RT) combined with surgery constitute the mainstay of therapy for local...
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Article
Open AccessFear of prognosis? How anxiety, co**, and expected burden impact the decision to have cytogenetic assessment in uveal melanoma patients
Cytogenetic testing (CGT) in uveal melanoma patients reveals prognostic information about the individual risk of develo** distant metastasis with dismal prognosis. There is currently no medical intervention ...
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Article
A web-based app to provide personalized recommendations for COVID-19
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Article
Correction to: Value of PET imaging for radiation therapy
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Article
Open AccessQuality of life and treatment-related burden during ocular proton therapy: a prospective trial of 131 patients with uveal melanoma
Proton beam therapy is a well-established treatment option for patients with uveal melanoma (UM). The treatment procedure, in general, includes placing radiopaque clips to ensure exact eye-positioning during r...
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Article
Value of PET imaging for radiation therapy
This comprehensive review written by experts in their field gives an overview on the current status of incorporating positron emission tomography (PET) into radiation treatment planning. Moreover, it highlight...
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Article
Open AccessComparison of the composition of lymphocyte subpopulations in non-relapse and relapse patients with squamous cell carcinoma of the head and neck before, during radiochemotherapy and in the follow-up period: a multicenter prospective study of the German Cancer Consortium Radiation Oncology Group (DKTK-ROG)
Radiochemotherapy (RCT) has been shown to induce changes in immune cell homeostasis which might affect antitumor immune responses. In the present study, we aimed to compare the composition and kinetics of majo...
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Article
Open AccessLong-term results of robotic radiosurgery for non brachytherapy patients with cervical cancer
Consolidation brachytherapy is a critical treatment component for cervical cancer patients undergoing primary chemoradiation. Some patients are unsuitable for brachytherapy for a variety of reasons. The use of...
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Article
Open AccessExternal application of liver compresses to reduce fatigue in patients with metastatic cancer undergoing radiation therapy, a randomized clinical trial
Liver compresses are frequently used in integrative medicine as supportive therapy during cancer treatment in order to reduce fatigue. We performed a pilot study to test whether the external application of yar...
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Article
Open AccessCorrection: ERCC2 gene single-nucleotide polymorphism as a prognostic factor for locally advanced head and neck carcinomas after definitive cisplatin-based radiochemotherapy
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
The rationale and development of a CyberKnife© registry for pediatric patients with CNS lesions
CyberKnife© Radiosurgery (CKRS) is a recognized treatment concept for CNS lesions in adults due to its high precision and efficacy beside a high patient comfort. However, scientific evidence for this treatment mo...
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Article
Open AccessERCC2 gene single-nucleotide polymorphism as a prognostic factor for locally advanced head and neck carcinomas after definitive cisplatin-based radiochemotherapy
Identifying patients with locally advanced head and neck carcinoma on high risk of recurrence after definitive concurrent radiochemotherapy is of key importance for the selection for consolidation therapy and ...
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Chapter and Conference Paper
Re-Irradiation for Local Relapses or Second Primaries: When and how?
With modern radiotherapy techniques, re-irradiation is a potentially curative treatment approach. However, it carries still a serious risk of severe radiation morbidity including treatment-related death. High-...
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Article
Open AccessPredicting survival in anaplastic astrocytoma patients in a single-center cohort of 108 patients
Current guidelines for the treatment of anaplastic astrocytoma (AA) recommend maximal safe resection followed by radiotherapy and chemotherapy. Despite this multimodal treatment approach, patients have a limit...
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Article
Open AccessCorrection to: Normofractionated stereotactic radiotherapy versus CyberKnife-based hypofractionation in skull base meningioma: a German and Italian pooled cohort analysis
An amendment to this paper has been published and can be accessed via the original article.
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Article
Open AccessRadiosurgery for ventricular tachycardia: preclinical and clinical evidence and study design for a German multi-center multi-platform feasibility trial (RAVENTA)
Single-session high-dose stereotactic radiotherapy (radiosurgery) is a new treatment option for otherwise untreatable patients suffering from refractory ventricular tachycardia (VT). In the initial single-cent...
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Article
Open AccessA FDG-PET radiomics signature detects esophageal squamous cell carcinoma patients who do not benefit from chemoradiation
Detection of patients with esophageal squamous cell carcinoma (ESCC) who do not benefit from standard chemoradiation (CRT) is an important medical need. Radiomics using 18-fluorodeoxyglucose (FDG) positron emi...
