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Article
CDC7-independent G1/S transition revealed by targeted protein degradation
The entry of mammalian cells into the DNA synthesis phase (S phase) represents a key event in cell division1. According to current models of the cell cycle, the kinase CDC7 constitutes an essential and rate-limit...
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Article
Open AccessMetallothionein-3 promotes cisplatin chemoresistance remodelling in neuroblastoma
Metallothionein-3 has poorly characterized functions in neuroblastoma. Cisplatin-based chemotherapy is a major regimen to treat neuroblastoma, but its clinical efficacy is limited by chemoresistance. We invest...
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Article
Open AccessImproving cytocompatibility of CdTe quantum dots by Schiff-base-coordinated lanthanides surface do**
Suitable fluorophores are the core of fluorescence imaging. Among the most exciting, yet controversial, labels are quantum dots (QDs) with their unique optical and chemical properties, but also considerable to...
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Article
Open AccessIdentification of Sarcosine as a Target Molecule for the Canine Olfactory Detection of Prostate Carcinoma
The hypothesis that dogs can detect malignant tumours through the identification of specific molecules is nearly 30 years old. To date, several reports have described the successful detection of distinct types...
